Caseware UK (AP4) 2025.0.111 2025.0.111 2025-12-312025-12-317truefalseThe principal activity of the Company is the research and development of novel approaches to Natural Killer (NK) cell-mediated immunotherapy. The company develops both cell therapy and small molecule therapeutics primarily targeting cancer, enabling physicians to target cancer more effectively.true72025-01-01The members have not required the company to obtain an audit in accordance with section 476 of the Companies Act 2006.false 12479455 2025-01-01 2025-12-31 12479455 2024-01-01 2024-12-31 12479455 2025-12-31 12479455 2024-12-31 12479455 c:Director9 2025-01-01 2025-12-31 12479455 d:CurrentFinancialInstruments 2025-12-31 12479455 d:CurrentFinancialInstruments 2024-12-31 12479455 d:CurrentFinancialInstruments d:WithinOneYear 2025-12-31 12479455 d:CurrentFinancialInstruments d:WithinOneYear 2024-12-31 12479455 d:ShareCapital 2025-12-31 12479455 d:ShareCapital 2024-12-31 12479455 d:SharePremium 2025-12-31 12479455 d:SharePremium 2024-12-31 12479455 d:RetainedEarningsAccumulatedLosses 2025-12-31 12479455 d:RetainedEarningsAccumulatedLosses 2024-12-31 12479455 c:OrdinaryShareClass1 2025-01-01 2025-12-31 12479455 c:OrdinaryShareClass1 2025-12-31 12479455 c:OrdinaryShareClass2 2025-01-01 2025-12-31 12479455 c:OrdinaryShareClass2 2025-12-31 12479455 c:OrdinaryShareClass3 2025-01-01 2025-12-31 12479455 c:OrdinaryShareClass3 2025-12-31 12479455 c:OrdinaryShareClass4 2025-01-01 2025-12-31 12479455 c:OrdinaryShareClass4 2025-12-31 12479455 c:FRS102 2025-01-01 2025-12-31 12479455 c:AuditExempt-NoAccountantsReport 2025-01-01 2025-12-31 12479455 c:FullAccounts 2025-01-01 2025-12-31 12479455 c:PrivateLimitedCompanyLtd 2025-01-01 2025-12-31 12479455 e:PoundSterling 2025-01-01 2025-12-31 iso4217:GBP xbrli:shares xbrli:pure

Registered number: 12479455









NK:IO LTD







UNAUDITED

FINANCIAL STATEMENTS

INFORMATION FOR FILING WITH THE REGISTRAR

FOR THE YEAR ENDED 31 DECEMBER 2025

 
NK:IO LTD
REGISTERED NUMBER: 12479455

BALANCE SHEET
AS AT 31 DECEMBER 2025

2025
2024
Note
£
£

  

CURRENT ASSETS
  

Debtors: amounts falling due within one year
 4 
2,904
195,329

Cash at bank and in hand
  
95,583
484,335

  
98,487
679,664

Creditors: amounts falling due within one year
 5 
(63,279)
(182,572)

NET CURRENT ASSETS
  
 
 
35,208
 
 
497,092

  

NET ASSETS
  
35,208
497,092


CAPITAL AND RESERVES
  

Called up share capital 
 6 
-
-

Share premium account
  
4,025,405
4,025,405

Profit and loss account
  
(3,990,197)
(3,528,313)

  
35,208
497,092


Page 1

 
NK:IO LTD
REGISTERED NUMBER: 12479455
    
BALANCE SHEET (CONTINUED)
AS AT 31 DECEMBER 2025

The directors consider that the Company is entitled to exemption from audit under section 477 of the Companies Act 2006 and members have not required the Company to obtain an audit for the year in question in accordance with section 476 of the Companies Act 2006.

The directors acknowledge their responsibilities for complying with the requirements of the Companies Act 2006 with respect to accounting records and the preparation of financial statements.

The financial statements have been prepared in accordance with the provisions applicable to companies subject to the small companies regime and in accordance with the provisions of FRS 102 Section 1A - small entities.

The financial statements have been delivered in accordance with the provisions applicable to companies subject to the small companies regime.

The Company has opted not to file the statement of comprehensive income in accordance with provisions applicable to companies subject to the small companies' regime.

The financial statements were approved and authorised for issue by the board and were signed on its behalf by: 




R A Hopkins
Director

Date: 30 June 2026

The notes on pages 3 to 6 form part of these financial statements.

Page 2

 
NK:IO LTD
 
 
 
NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 31 DECEMBER 2025

1.


GENERAL INFORMATION

NK:IO Ltd is a private company limited by shares incorporated in England and Wales. The registered office address is Mishcon De Reya, Africa House, 70 Kingsway, London, WC2B 6AH.
 

2.ACCOUNTING POLICIES

 
2.1

BASIS OF PREPARATION OF FINANCIAL STATEMENTS

The financial statements have been prepared under the historical cost convention unless otherwise specified within these accounting policies and in accordance with Financial Reporting Standard 102, the Financial Reporting Standard applicable in the UK and the Republic of Ireland and the requirements and the Companies Act 2006. The disclosure requirements of Section 1A of FRS 102 have been applied other than where additional disclosure is required to show a true and fair view.

The following principal accounting policies have been applied:

 
2.2

GOING CONCERN

The financial statements have been prepared on the going concern basis which assumes that the Company will continue as a going concern for the foreseeable future. The trading losses reported to date are consistent with the Company's business plan as it progresses its research and development activities.

The directors have reviewed the Company’s future cash flows following the agreement of deferred payment plans with its creditors. Based on this assessment, the directors have a reasonable expectation that the Company will be able to meet its liabilities as they fall due for the foreseeable future. Accordingly, they continue to adopt the going concern basis in preparing the financial statements.

 
2.3

FOREIGN CURRENCY TRANSLATION

Functional and presentation currency

The Company's functional and presentational currency is GBP.

Transactions and balances

Foreign currency transactions are translated into the functional currency using the spot exchange rates at the dates of the transactions.

At each period end foreign currency monetary items are translated using the closing rate. Non-monetary items measured at historical cost are translated using the exchange rate at the date of the transaction and non-monetary items measured at fair value are measured using the exchange rate when fair value was determined.

Foreign exchange gains and losses resulting from the settlement of transactions and from the translation at period-end exchange rates of monetary assets and liabilities denominated in foreign currencies are recognised in profit or loss except when deferred in other comprehensive income as qualifying cash flow hedges.

Foreign exchange gains and losses that relate to borrowings and cash and cash equivalents are presented in the Statement of Comprehensive Income within 'finance income or costs'. All other foreign exchange gains and losses are presented in profit or loss within 'other operating income'.

Page 3

 
NK:IO LTD
 
 
 
NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 31 DECEMBER 2025

2.ACCOUNTING POLICIES (CONTINUED)

 
2.4

PENSIONS

DEFINED CONTRIBUTION PENSION PLAN

The Company operates a defined contribution plan for its employees. A defined contribution plan is a pension plan under which the Company pays fixed contributions into a separate entity. Once the contributions have been paid the Company has no further payment obligations.

The contributions are recognised as an expense in profit or loss when they fall due. Amounts not paid are shown in accruals as a liability in the Balance Sheet. The assets of the plan are held separately from the Company in independently administered funds.

 
2.5

DEBTORS

Short-term debtors are measured at transaction price, less any impairment. Loans receivable are measured initially at fair value, net of transaction costs, and are measured subsequently at amortised cost using the effective interest method, less any impairment.

 
2.6

CASH AND CASH EQUIVALENTS

Cash is represented by cash in hand and deposits with financial institutions repayable without penalty on notice of not more than 24 hours. Cash equivalents are highly liquid investments that mature in no more than three months from the date of acquisition and that are readily convertible to known amounts of cash with insignificant risk of change in value.

 
2.7

CREDITORS

Short-term creditors are measured at the transaction price. Other financial liabilities, including bank loans, are measured initially at fair value, net of transaction costs, and are measured subsequently at amortised cost using the effective interest method.

 
2.8

RESEARCH AND DEVELOPMENT

Research and development expenditure is recognised in the Profit and Loss Account in the period in which the expenditure is incurred.

Page 4

 
NK:IO LTD
 
 
 
NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 31 DECEMBER 2025

2.ACCOUNTING POLICIES (CONTINUED)

 
2.9

TAXATION

Tax is recognised in profit or loss except that a charge attributable to an item of income and expense recognised as other comprehensive income or to an item recognised directly in equity is also recognised in other comprehensive income or directly in equity respectively.

The current income tax charge is calculated on the basis of tax rates and laws that have been enacted or substantively enacted by the balance sheet date in the countries where the Company operates and generates income.


Deferred tax balances are recognised in respect of all timing differences that have originated but not reversed by the Balance Sheet date, except that:

- The recognition of deferred tax assets is limited to the extent that it is probable that they will be recovered against the reversal of deferred tax liabilities or other future taxable profits; and

- Any deferred tax balances are reversed if and when all conditions for retaining associated tax allowances have been met.

Deferred tax balances are not recognised in respect of permanent differences. Deferred tax is determined using tax rates and laws that have been enacted or substantively enacted by the balance sheet date.


3.


EMPLOYEES

The average monthly number of employees, including directors, during the year was 7 (2024 - 7).


4.


DEBTORS: AMOUNTS FALLING DUE WITHIN ONE YEAR

2025
2024
£
£

Other debtors
2,668
37,864

Prepayments and accrued income
236
157,465

2,904
195,329


Page 5

 
NK:IO LTD
 
 
 
NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 31 DECEMBER 2025

5.


CREDITORS: AMOUNTS FALLING DUE WITHIN ONE YEAR

2025
2024
£
£

Trade creditors
60,219
102,733

Other taxation and social security
-
4,399

Accruals and deferred income
3,060
75,440

63,279
182,572



6.


SHARE CAPITAL

2025
2024
£
£
ALLOTTED, CALLED UP AND FULLY PAID



1,249,569 (2024 - 1,249,569) Ordinary shares of £0.000000001 each
-
-
435,745 (2024 - 435,745) T Ordinary shares of £0.000000001 each
-
-
2,442,798 (2024 - 2,442,798) Seed shares of £0.000000001 each
-
-
109,914 (2024 - 109,914) Deferred shares of £0.000000001 each
-
-

-

-

The aggregate nominal value of the above issued shares is £0.004238026.


 
Page 6