Registered number
09496393 (England & Wales)
Replimune Limited
Annual Report and Financial Statements
31 March 2026
Replimune Limited
Annual report and financial statements
Contents
Page(s)
Company Information 1
Strategic Report 2 to 4
Directors' Report 5 to 6
Independent auditors' report to the members of Replimune Limited 7 to 10
Statement of Comprehensive Income 11
Statement of Financial Position 12 to 13
Statement of Changes in Equity 14
Statement of Cash Flows 15
Notes to the Financial Statements 16 to 34
Replimune Limited
Company Information
Directors
S Glidden
E Hill
S Patel
Independent auditors
PricewaterhouseCoopers LLP
One Station Hill
Garrard Street
Reading
Berkshire
RG1 1NR
United Kingdom
Registered office
69 Innovation Drive
Milton Park
Abingdon
Oxfordshire
OX14 4RQ
United Kingdom
Registered number
09496393
Replimune Limited
Strategic report
The directors present their report for the year ended 31 March 2026.
Business environment
Replimune is a clinical-stage biotech company focused on revolutionizing cancer treatment with a new class of oncolytic immunotherapies intended to activate a powerful and durable full-body anti-tumor response. Replimune’s proprietary RPx platform is based on a potent Herpes Simplex Virus Type 1(HSV-1) backbone. The virus is then armed with further specific genes and therapeutic transgenes to stimulate further anti tumor activity and also to stimulate the patients’ immune system. The RPx product candidates are expected to be synergistic with most established and experimental cancer treatment modalities, leading to the versatility to be developed alone or combined with a variety of other treatment options.
Whilst continuing to support ongoing development and clinical studies, Replimune is aiming to launch the first product in Q4 2026 for the treatment of advanced melanoma. Melanoma is the fifth most common cancer in the United States, with approximately 112,000 new cases estimated in 2026 and the most lethal form of skin cancer, accounting for nearly 8,500 deaths annually. Melanoma is considered advanced when the cancer has spread beyond the primary tumor. Standard of care therapy includes immune checkpoint blockade, to which approximately half of patients will not respond or will progress after treatment, leaving a significant population in need of effective therapeutic alternatives.
Strategy
Replimune utilise a modified version of the herpes simplex virus type 1, the virus that generally causes cold sores or fever blisters which has been engineered to selectively replicate in cancer / tumor cells as the backbone of the platform technology. RP1 (vusolimogene oderparepvec) is Replimune's lead product candidate, the platform virus is encoded with a fusogenic protein (GALV-GP R-) and Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF). Pivotal clinical trials have been completed for anti-PD1 (Programmed cell death protein 1) failed Melanoma demonstrating reduction in tumors both local to the injection sites and systemically around the body including in patients who have progressed on prior treatment with anti-PD1. Oncolytic immunotherapies of this nature are designed to work by directly destroying the injected tumours and altering the tumor microenvironment thereby releasing further tumor derived antigens. Despite the patients failing to respond to the anti-PD1 check point inhibitors alone, our initial clinical trials have progressed using the therapy in combination with further anti-PD1 check point inhibitor such as Nivolumab to maximise the potential patients’ immune response.
Replimune submitted a biological license application (BLA) with the Food and Drug Administration (FDA) for RP1 (vusolimogene oderparepvec) in combination with nivolumab for the treatment of advanced melanoma in late 2024. The application was accepted in January 2025 granting expediated review with a PDUFA (Prescription Drug User Fee Act) date in July 2025. This submission was initially rejected but the FDA accepted a re-submission of the licence application on 20th Oct 2025 with an action date of 10th April. A complete response letter (CRL) was received ahead of a further resubmission with an action date of 2nd August 2026.
Whilst the regulatory review process remains ongoing, the business maintains the intent to commercially launch RP1 in the US for this indication.
Replimune is also developing further product candidates on this platform. The second product RP2 additionally codes for an anti CTLA-4 (Cytotoxic T-lymphocyte-associated protein 4) antibody has been optimally designed to treat more immunologically silent tumors. Phase 1 and 2 trials have been initiated for HCC (Hepatocellular Carcinoma) and Uveal melanoma.
The Company has sought no financial assistance, either in the form of government support grants or in government supported loan funding and has no future intentions in this respect. The Company continues to prepare for commercial readiness.
Overall business performance and Key Performance Indicators
In combination with the parent company, the Company has established a full in house manufacturing capability for the RPx platform.
The US manufacturing and UK testing facility were subject to successful Pre Approval inspections by the FDA.
At the end of this reporting period the UK headcount was 72 with recruitment ongoing for an additional 8 roles. In the period subsequent period the headcount was adjusted post 2nd CRL pending further feedback from the FDA on the resubmission.
Overall business risk
The principal risks and uncertainties to the business concerns the sufficiency of funding to progress its programs through to market.
The Company has also received assurances that it will receive financial support from its ultimate parent company, Replimune Group, Inc., as required. At 31 March 2026, the existence of a material uncertainty which may cast significant doubt about the Company’s ability to continue as a going concern has been identified, see note 3 for further details on the going concern position of the Company.
The Company received $264,883,183 (2025: $256,424,182) from its ultimate parent company as a capital contribution in the year ended 31 March 2026. The directors believe, based on their knowledge of the Replimune group, that this support will continue to be available if it is needed.
The balance at bank as at 31 March 2026 was $4,439,720 (2025: $2,393,424).
Financial risk and capital management
The Company’s activities expose it to a number of financial risks, specifically foreign exchange risk and liquidity risk. The group’s overall risk management programme focuses on the unpredictability of financial markets and seeks to minimise potential adverse effects on the Company's financial performance.
The board develops the principles for overall risk management and carries out the risk management programme focussing on the major risks identified, these are not considered to have a material impact.
Foreign exchange risk
The Company undertakes transactions denominated in foreign currencies and holds funds in US Dollars; consequently, exposures to exchange rate fluctuations arise. The board considers the relative cash holdings in US Dollars and £ Sterling on a regular basis.
Liquidity and cash flow risk
Short and medium term cash flow forecasting is performed on a regular basis to ensure that sufficient cash is on hand to meet operational needs, such forecasting having regard to the progression of the lead product towards the required regulatory approval. The Company has also received assurances that it will receive financial support from its ultimate parent company, Replimune Group, Inc., as required. At 31 March 2026, the existence of a material uncertainty which may cast significant doubt about the Company’s ability to continue as a going concern has been identified, see note 3 for further details on the going concern position of the company.
Financial risk and capital management (continued)
Capital management
The capital structure of the Company is as disclosed in note 18. The Company's objectives are to manage the capital in such a manner as to safeguard the Company's ability to continue as a going concern.
There is no debt in the form of borrowings and the Company is not subject to any externally imposed capital requirements. The Company monitors capital on a regular basis in order to anticipate any future significant variations in capital.
The ultimate parent company provides funds to the Company on a regular basis as required.
Critical accounting estimates and judgements
The Company makes estimates and judgements concerning the future. The resulting accounting estimates will, by definition, seldom equal the related actual results.
There are no estimates and assumptions that have a significant risk of causing a material adjustment to the carrying amounts of assets and liabilities within the next financial year.
This report was approved by the board and signed on its behalf by:
S Glidden
Director
Approved on: 15 July 2026
Replimune Limited
Directors' Report
The directors present their report and the audited financial statements for the year ended 31 March 2026.
General information
The Company is a private company limited by shares, incorporated in England and is domiciled in the United Kingdom. The registered office and principal place of business is: 69 Innovation Drive, Milton Park, Abingdon, Oxfordshire, OX14 4RQ, United Kingdom. The Company is a wholly owned subsidiary of its ultimate parent company Replimune Group, Inc.
Principal activities
The Company was incorporated on 18 March 2015 as an investor-funded research and development company, based in the UK and with a US corporate parent and support office. The Company specialises in developing an emerging class of cancer therapeutics, known as oncolytic immunotherapy.
Results for the year
The Company made a loss for the year of $247,674,374 (2025: $214,693,315). The Company also had net liabilities of $18,311,674 (2025: $34,943,259).
Dividends
The directors are unable to recommend a final dividend (2025: $nil) as there were accumulated losses at the end of the financial year.
Directors
The directors of the Company who were in office during the year and up to the date of signing the financial statements, unless otherwise stated, were:
S Glidden
E Hill
S Patel
All the directors who are eligible offer themselves for election at the forthcoming Annual General Meeting.
Future developments and research and development
For details of the Company's expected future developments and research and development activities, please see the "strategy" section of the strategic report.
Financial instruments
The financial risk management objectives and policies of the entity and the exposure of the entity to liquidity risk and cash flow risk are included within the "Financial risk and capital management" section of the strategic report. There are no material risks to the Company in relation to price risk and credit risk.
Statement of directors’ responsibilities in respect of the financial statements
The directors are responsible for preparing the Annual report and the financial statements in accordance with applicable law and regulation.
Company law requires the directors to prepare financial statements for each financial year. Under that law the directors have prepared the financial statements in accordance with UK-adopted international accounting standards.
Under company law, directors must not approve the financial statements unless they are satisfied that they give a true and fair view of the state of affairs of the Company and of the profit or loss of the Company for that period. In preparing the financial statements, the directors are required to:
select suitable accounting policies and then apply them consistently;
state whether applicable UK-adopted international accounting standards have been followed, subject to any material departures disclosed and explained in the financial statements;
make judgements and accounting estimates that are reasonable and prudent; and
prepare the financial statements on the going concern basis unless it is inappropriate to presume that the company will continue in business.
The directors are also responsible for safeguarding the assets of the Company and hence for taking reasonable steps for the prevention and detection of fraud and other irregularities.
The directors are responsible for keeping adequate accounting records that are sufficient to show and explain the Company’s transactions and disclose with reasonable accuracy at any time the financial position of the Company and enable them to ensure that the financial statements comply with the Companies Act 2006.
Directors' confirmations
In the case of each director in office at the date the directors' report is approved:
so far as the director is aware, there is no relevant audit information of which the Company’s auditors are unaware; and
they have taken all the steps that they ought to have taken as a director in order to make themselves aware of any relevant audit information and to establish that the Company’s auditors are aware of that information.
Independent auditors
The independent auditors, PricewaterhouseCoopers LLP, have expressed their willingness to continue in office and a resolution to reappoint them will be proposed at the annual general meeting.
Qualifying third party indemnity provisions
As permitted by the Articles of Association, the directors have the benefit of an indemnity which is a qualifying third party indemnity provision as defined by Section 234 of the Companies Act 2006. The indemnity was in force throughout the financial year and at the date of the approval of the financial statements. The Company also purchased and maintained throughout the financial year and at the date of the approval of the financial statements: Directors’ and Officers’ Liability insurance, in respect of itself and of its directors.
This report was approved by the board and signed on its behalf by:
S Glidden
Director
Approved on: 15 July 2026
Independent auditors' report to the members of Replimune Limited
Report on the audit of the financial statements
Opinion
In our opinion, Replimune Limited's financial statements:
give a true and fair view of the state of the company's affairs as at 31 March 2026 and of its loss and cash flows for the year then ended;
have been properly prepared in accordance with UK-adopted international accounting standards; and
have been prepared in accordance with the requirements of the Companies Act 2006.
We have audited the financial statements, included within the Annual Report and Financial Statements (the "Annual Report"), which comprise:
the Statement of Financial Position as at 31 March 2026;
the Statement of Comprehensive Income for the year then ended;
the Statement of Changes in Equity for the year then ended;
the Statement of Cash Flows for the year then ended; and
the notes to the financial statements, comprising material accounting policy information and other explanatory information.
Basis for opinion
We conducted our audit in accordance with International Standards on Auditing (UK) ("ISAs (UK)") and applicable law. Our responsibilities under ISAs (UK) are further described in the Auditors’ responsibilities for the audit of the financial statements section of our report. We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis for our opinion.
Independence
We remained independent of the company in accordance with the ethical requirements that are relevant to our audit of the financial statements in the UK, which includes the FRC’s Ethical Standard, and we have fulfilled our other ethical responsibilities in accordance with these requirements.
Material uncertainty related to going concern
In forming our opinion on the financial statements, which is not modified, we have considered the adequacy of the disclosure made in note 3 to the financial statements concerning the company’s ability to continue as a going concern. The company is reliant on financial support from the Group and the Group will need to raise additional funding by the first quarter of 2027 in order to continue its planned operations, which has not yet been secured.
These conditions, along with the other matters explained in note 3 to the financial statements, indicate the existence of a material uncertainty which may cast significant doubt about the company's ability to continue as a going concern. The financial statements do not include the adjustments that would result if the company were unable to continue as a going concern.
In auditing the financial statements, we have concluded that the directors' use of the going concern basis of accounting in the preparation of the financial statements is appropriate.
Our responsibilities and the responsibilities of the directors with respect to going concern are described in the relevant sections of this report.
Independent auditors' report
to the members of Replimune Limited (continued)
Reporting on other information
The other information comprises all of the information in the Annual Report other than the financial statements and our auditors’ report thereon. The directors are responsible for the other information. Our opinion on the financial statements does not cover the other information and, accordingly, we do not express an audit opinion or, except to the extent otherwise explicitly stated in this report, any form of assurance thereon.
In connection with our audit of the financial statements, our responsibility is to read the other information and, in doing so, consider whether the other information is materially inconsistent with the financial statements or our knowledge obtained in the audit, or otherwise appears to be materially misstated. If we identify an apparent material inconsistency or material misstatement, we are required to perform procedures to conclude whether there is a material misstatement of the financial statements or a material misstatement of the other information. If, based on the work we have performed, we conclude that there is a material misstatement of this other information, we are required to report that fact. We have nothing to report based on these responsibilities.
With respect to the Strategic report and Directors' Report, we also considered whether the disclosures required by the Companies Act 2006 have been included.
Based on our work undertaken in the course of the audit, the Companies Act 2006 requires us also to report certain opinions and matters as described below.
Strategic report and Directors’ Report
In our opinion, based on the work undertaken in the course of the audit, the information given in the Strategic report and Directors' Report for the year ended 31 March 2026 is consistent with the financial statements and has been prepared in accordance with applicable legal requirements.
In light of the knowledge and understanding of the company and its environment obtained in the course of the audit, we did not identify any material misstatements in the Strategic report and Directors' Report.
Responsibilities for the financial statements and the audit
Responsibilities of the directors for the financial statements
As explained more fully in the Statement of directors’ responsibilities in respect of the financial statements, the directors are responsible for the preparation of the financial statements in accordance with the applicable framework and for being satisfied that they give a true and fair view. The directors are also responsible for such internal control as they determine is necessary to enable the preparation of financial statements that are free from material misstatement, whether due to fraud or error.
In preparing the financial statements, the directors are responsible for assessing the company's ability to continue as a going concern, disclosing, as applicable, matters related to going concern and using the going concern basis of accounting unless the directors either intend to liquidate the company or to cease operations, or have no realistic alternative but to do so.
Independent auditors' report
to the members of Replimune Limited (continued)
Responsibilities for the financial statements and the audit (continued)
Auditors’ responsibilities for the audit of the financial statements
Our objectives are to obtain reasonable assurance about whether the financial statements as a whole are free from material misstatement, whether due to fraud or error, and to issue an auditors’ report that includes our opinion. Reasonable assurance is a high level of assurance, but is not a guarantee that an audit conducted in accordance with ISAs (UK) will always detect a material misstatement when it exists. Misstatements can arise from fraud or error and are considered material if, individually or in the aggregate, they could reasonably be expected to influence the economic decisions of users taken on the basis of these financial statements.
Irregularities, including fraud, are instances of non-compliance with laws and regulations. We design procedures in line with our responsibilities, outlined above, to detect material misstatements in respect of irregularities, including fraud. The extent to which our procedures are capable of detecting irregularities, including fraud, is detailed below.
Based on our understanding of the company and industry, we identified that the principal risks of non-compliance with laws and regulations related to Companies Act 2006 and tax legislation, and we considered the extent to which non-compliance might have a material effect on the financial statements. We evaluated management’s incentives and opportunities for fraudulent manipulation of the financial statements (including the risk of override of controls), and determined that the principal risks were related to misappropriation of cash. Audit procedures performed by the engagement team included:
Inquiries of management to identify any known or suspected instances of non compliance with laws and regulations and fraud;
Evaluation of management's controls designed to prevent and detect irregularities;
Testing journal entries posted with unusual account combinations which credit cash;
Reading Board meeting minutes to determine if any known or suspected fraud or non-compliance with laws and regulations have been identified;
Incorporating an element of unpredictability into our audit; and
Performing a review of financial statement disclosures for compliance with Companies Act 2006.
There are inherent limitations in the audit procedures described above. We are less likely to become aware of instances of non-compliance with laws and regulations that are not closely related to events and transactions reflected in the financial statements. Also, the risk of not detecting a material misstatement due to fraud is higher than the risk of not detecting one resulting from error, as fraud may involve deliberate concealment by, for example, forgery or intentional misrepresentations, or through collusion.
A further description of our responsibilities for the audit of the financial statements is located on the FRC's website at: www.frc.org.uk/auditorsresponsibilities. This description forms part of our auditors' report.
Use of this report
This report, including the opinions, has been prepared for and only for the company's members as a body in accordance with Chapter 3 of Part 16 of the Companies Act 2006 and for no other purpose. We do not, in giving these opinions, accept or assume responsibility for any other purpose or to any other person to whom this report is shown or into whose hands it may come save where expressly agreed by our prior consent in writing.
Independent auditors' report
to the members of Replimune Limited (continued)
Other required reporting
Companies Act 2006 exception reporting
Under the Companies Act 2006 we are required to report to you if, in our opinion:
we have not obtained all the information and explanations we require for our audit; or
adequate accounting records have not been kept by the company or returns adequate for our audit have not been received from branches not visited by us; or
the company's financial statements are not in agreement with the accounting records and returns; or
certain disclosures of directors's remuneration specified by law are not made.
We have no exceptions to report arising from this responsibility.
Ruth Ashman-Wutte (Senior Statutory Auditor)
for and on behalf of PricewaterhouseCoopers LLP
Chartered Accountants and Statutory Auditors
Reading
16 July 2026
Replimune Limited
Statement of Comprehensive Income
for the year ended 31 March 2026
Note 2026 2025
$ $
Research and development expenditure (219,819,317) (194,810,476)
Administrative expenses (29,029,224) (21,789,413)
Other (losses)/gains 7 (256,516) 343,563
Operating loss 8 (249,105,057) (216,256,326)
Finance income 9 75,262 70,209
Finance costs 10 (248,767) (279,833)
Loss on ordinary activities before taxation (249,278,562) (216,465,950)
Income tax 11 1,604,188 1,772,635
Loss for the financial year (247,674,374) (214,693,315)
Total comprehensive loss for the financial year (247,674,374) (214,693,315)
All operations relate to continuing operations.
The notes on pages 16 to 34 are an integral part of the financial statements.
Replimune Limited Registered number: 09496393 (England & Wales)
Statement of Financial Position
as at 31 March 2026
Note 2026 2025
$ $
Assets
Non-current assets
Property, plant and equipment 12 2,280,837 2,731,378
Investment in subsidiary 13 - -
2,280,837 2,731,378
Current assets
Prepayments and other receivables 14 792,569 1,108,629
Current tax receivable 15 3,360,927 3,724,980
Cash and cash equivalents 4,439,720 2,393,424
8,593,216 7,227,033
Total assets 10,874,053 9,958,411
Equity and liabilities
Liabilities
Non current liabilities
Lease liabilities 16 1,022,508 1,277,015
1,022,508 1,277,015
Current liabilities
Trade and other payables 17 28,163,219 43,624,655
28,163,219 43,624,655
Total liabilities 29,185,727 44,901,670
Net liabilities (18,311,674) (34,943,259)
Equity
Called up share capital 18 1,499 1,499
Share premium 32,061,169 32,061,169
Capital contribution reserve 996,199,220 731,893,261
Cumulative translation adjustment (8,677,550) (8,677,550)
Accumulated losses (1,037,896,012) (790,221,638)
Total equity (18,311,674) (34,943,259)
Total equity and liabilities 10,874,053 9,958,411
The financial statements on pages 11 to 34 were approved and authorised for issue by the board of directors and were signed and dated on its behalf by:
S Glidden Dated: 15 July 2026
Director
The notes on pages 16 to 34 are an integral part of the financial statements.
Replimune Limited
Statement of Changes in Equity
for the year ended 31 March 2026
Called up Capital Cumulative translation adjustment
share Share contribution Accumulated Total
capital premium reserve losses equity
(Note 18)
$ $ $ $ $ $
At 1 April 2024 1,499 32,061,169 476,933,053 (8,677,550) (575,528,323) (75,210,152)
Loss and total comprehensive loss for the financial year - - - - (214,693,315) (214,693,315)
Capital contribution from parent company - - 256,424,182 - - 256,424,182
Equity settled transactions - reversal of US GAAP recharge - - (2,090,743) - - (2,090,743)
Equity settled transactions - IFRS 2 charge - - 626,769 - - 626,769
At 31 March 2025 1,499 32,061,169 731,893,261 (8,677,550) (790,221,638) (34,943,259)
At 1 April 2025 1,499 32,061,169 731,893,261 (8,677,550) (790,221,638) (34,943,259)
Loss and total comprehensive loss for the financial year - - - - (247,674,374) (247,674,374)
Capital contribution from parent company - - 264,883,183 - - 264,883,183
Equity settled transactions - reversal of US GAAP recharge - - (2,105,213) - - (2,105,213)
Equity settled transactions - IFRS 2 charge - - 1,527,989 - - 1,527,989
At 31 March 2026 1,499 32,061,169 996,199,220 (8,677,550) (1,037,896,012) (18,311,674)
Movements in the capital contribution from the parent company in the year comprise the following:
- Receipt of $264,883,183 (2025: $256,424,182) from the ultimate parent company (Replimune Group, Inc.), throughout the year.
- Reversal of the share based payment recharge of $2,105,213 (2025: $2,090,743) received from Replimune Group, Inc.;
- calculated under United States Generally Accepted Accounting Practice (US GAAP).
- Share based payment charge for share options issued to Replimune Limited employees of $1,527,989 (2025: $626,769);
- calculated under IFRS.
The notes on pages 16 to 34 are an integral part of the financial statements.
Replimune Limited
Statement of Cash Flows
for the year ended 31 March 2026
Note
2026 2025
$ $
Cash flows from operating activities
Payments to group undertaking (247,467,201) (243,307,732)
Payments for interest portion of lease liabilities 16 (248,767) (279,833)
Payments to suppliers and employees (16,155,126) (15,036,316)
Cash used in operations (263,871,094) (258,623,881)
Income taxes received 2,052,329 3,116,824
Net cash outflow from operating activities (261,818,765) (255,507,057)
Cash flows from investing activities
Interest received 75,262 70,209
Payments to acquire property, plant and equipment (403,661) (273,627)
Cash used in investing activities (328,399) (203,418)
Cash flows from financing activities
Payments for principal portion of lease liabilities 16 (433,286) (272,737)
Capital contribution from parent undertaking 264,883,183 256,424,182
Cash generated by financing activities 264,449,897 256,151,445
Net increase in cash and cash equivalents 2,302,733 440,970
Cash and cash equivalents at the beginning of the
financial year
2,393,424 1,752,703
Exchange (loss)/gain on cash and cash equivalents (256,437) 199,751
Cash and cash equivalents at the end of the financial year:
Cash at bank 4,439,720 2,393,424
The notes on pages 16 to 34 are an integral part of the financial statements.
Replimune Limited
Notes to the Financial Statements
for the year ended 31 March 2026
1 General information
Replimune Limited (the "Company") is a private company limited by shares incorporated and domiciled in England. The Company has an immediate and ultimate parent company, Replimune Group, Inc., a company incorporated in the United States of America. The addresses of its registered office and principal place of business, and its principal activities are disclosed in the Directors' Report.
2 Functional currency for statutory reporting
Management regularly evaluate the functional currency to determine if there are any circumstances which would indicate the need for a change in the functional currency. The examination of the primary and secondary indicators in line with IAS 21 lead management to conclude that it was appropriate under IAS 21 to change the functional currency for the Replimune Limited statutory accounts from £ Sterling to US Dollars. Management elected to change the Company's presentational currency from £ Sterling to US Dollars, with both changes effective from the year ended 31 March 2023.
The change in presentational currency from £ Sterling to US Dollars was applied retrospectively such that the previously reported accumulated loss in £ Sterling at 31 March 2021 was translated into US Dollars at the relevant average annual historical exchange rate and as a result a Cumulative Translation Adjustment arose. The Cumulative Translation Adjustment would be reclassified from Equity to the Statement of Comprehensive Income upon the disposal of the business.
US Dollar denominated transactions arising during the years ended 31 March 2026 and 31 March 2025 are maintained at their US Dollar original value and all other transactions are retranslated to US Dollars using the average rate for the month.
The year end closing figures are translated at the US Dollar spot rate for monetary assets and liabilities, with non monetary assets and liabilities held using a historical cost basis.
3 Material accounting policies
Basis of preparation
(i) Compliance with IFRS
The financial statements of Replimune Limited have been prepared in accordance with UK-adopted international accounting standards and with the requirements of the Companies Act 2006 as applicable to companies reporting under those standards.
(ii) Historical cost convention
The financial statements have been prepared on a historical cost basis, except for tax credit receivable which is measured at fair value.
3 Material accounting policies (continued)
(iii) New and amended standards adopted by the Company
The Company has applied the following amendments for the first time for its annual reporting period commencing 1 April 2025:
- Amendments to IAS21 - Lack of Exchangeability
The Company has not elected to adopt any amendments early.
The amendments listed above did not have any impact on the amounts recognised in prior periods and are not expected to significantly affect the current or future periods.
The accounting policies have been applied consistently, other than where new policies have been adopted.
(iv) New standards and interpretations not yet adopted
Certain new accounting standards and interpretations have been published that are not mandatory for 31 March 2026 reporting periods and have not been early adopted by the Company. These standards are not expected to have a material impact on the entity in the current or future reporting periods and on foreseeable future transactions.
(v) Going concern
The ability of the Company to continue as a going concern is contingent on the ongoing viability of the ultimate parent company. The Company has received written assurances that it will receive financial support from Replimune Group, Inc. (the “Group”), either in the form of short-term loans and/or additional equity to enable it to meet its liabilities as they fall due for a period of at least 12 months from the date of approval of these financial statements.
Based on its current operating plan, the Group expects to continue to generate operating losses for the foreseeable future and that its existing cash, cash equivalents and short-term investments will be sufficient to fund its operating expenses and capital expenditure requirements only into the first calendar quarter of 2027, which is less than one year from the date these financial statements are issued. The Group does not have any committed source of additional funding and will be required to obtain additional financing to fund its operations beyond that date.
Currently, the Group is collaborating with the FDA regarding a path forward for RP1 and, if the BLA is approved, the Group will determine the best source of capital, which may be raising additional capital through public or private equity offerings (including under our at-the-market facilities), although there can be no guarantee that the Group will be able to raise such capital on acceptable terms, or at all. If the BLA is not approved, the Group will likely need to; (i) execute a considerable restructuring and workforce reduction to reduce their cash burn, (ii) reconsider their product development efforts and strategies, and (iii) pursue collaborations, strategic alliances, licensing arrangements, business combination, merger or acquisition, or other strategic business development activities in order to continue operations.
As such, these circumstances indicate the existence of a material uncertainty which may cast significant doubt about the Company's ability to continue as a going concern. These financial statements do not include the adjustments that would result if the Company was unable to continue as a going concern.
3 Material accounting policies (continued)
Property, plant and equipment
These assets are measured at cost less accumulated depreciation and any accumulated impairment losses.
For right of use assets, cost comprises an amount equal to the initial lease liability recognised, adjusted to include any payments for the right to use the asset, initial direct costs incurred and estimated costs for dismantling, removing and restoring the asset at the end of the lease term. Lease incentives receivable from the lessor are recognised as a reduction in costs. Depreciation on right of use assets is charged on a straight-line basis over the shorter of the useful economic life of the asset and the lease term.
Depreciation is provided on all property, plant and equipment, other than freehold land, at rates calculated to write off the cost, less estimated residual value, of each asset evenly over its expected useful life, as follows:
Improvements to leasehold premises : 33% on cost
Fixtures, fittings, tools and equipment : 20% on cost
Right of use asset: Property : shorter of the asset's useful life and the lease term on a straight-line basis
Assets under construction are carried at cost until works are complete and assets can be capitalised and depreciated in accordance with the applicable accounting policy.
The residual values, useful lives and methods of depreciation of property, plant and equipment are reviewed at each financial year end and adjusted prospectively, if appropriate.
Impairment of non-financial assets
The Company assesses at each reporting date whether there is an indication that an asset may be impaired. If any indication exists, the Company estimates the asset's recoverable amount.
An asset's recoverable amount is the higher of an asset's fair value less costs of disposal and its value in use. It is determined for an individual asset, unless the asset does not generate cash inflows that are largely independent of those from other assets or groups of assets. Where cash inflows are not independent for an individual asset, they are grouped at the lowest levels for which there are separately identifiable cash inflows. Where the carrying amount of an asset exceeds its recoverable amount, the asset is considered impaired and is written down to its recoverable amount.
3 Material accounting policies (continued)
Cash and cash equivalents
Cash is represented by cash deposits with financial institutions repayable without penalty on notice of not more than 24 hours. Cash equivalents are highly liquid investments that mature in no more than three months from the date of acquisition and that are readily convertible to known amounts of cash with insignificant risk of change in value.
Financial instruments - initial recognition and subsequent measurement
A financial instrument is any contract that gives rise to a financial asset of one entity and a financial liability or equity instrument of another entity. The carrying value of the financial instruments as of 31 March, 2026, approximates the fair value.
Financial assets
All financial assets, such as other receivables, are measured at amortised cost as these assets are held with the objective to collect the contractual cash flows and the contractual terms of the financial assets give rise to cash flows that are solely payments of principal and interest. There are no trade receivables as at 31 March 2026 or at 31 March 2025. Other receivables are measured at fair value, typically transaction price and subsequently measured at amortised cost less any impairment. Interest income from these financial assets is included in finance income using the effective interest rate method.
Impairment of financial assets
The Company assesses, at each reporting date, whether there is any objective evidence that a financial asset or a group of financial assets is impaired. An impairment exists if one or more events that has occurred since the initial recognition of the asset (an incurred 'loss event'), has an impact on the estimated future cash flows of the financial asset or the group of financial assets that can be reliably estimated. Impairment losses are presented within the relevant expense category to which the asset relates in profit or loss.
Financial liabilities
The Company's financial liabilities include trade and other payables. All financial liabilities are recognised initially at fair value.
(a) Trade and other payables
Trade and other payables are obligations to pay for goods or services that have been acquired in the ordinary course of business from suppliers. They are recognised initially at fair value and subsequently measured at amortised cost using the effective interest method.
Share capital
Ordinary, Seed Preferred and Series A shares are classified as equity. Any legal and professional fees associated with the issue of new ordinary shares or options are treated as an administrative expense.
3 Material accounting policies (continued)
Share-based payments
The ultimate parent company, Replimune Group, Inc., has issued equity settled share-based awards (also referred to as "share options" herein) to certain employees of Replimune Limited. The charge relating to these awards in respect of employees of the company has been reflected in these financial statements in accordance with IFRS 2 'Share-based Payment' although they do not relate to the shares of the company. A fair value for the equity settled share awards is measured at the date of grant, and this is recognised as a charge to the Statement of Comprehensive Income over the vesting period. The fair value of the options granted exclude the impact of any service and non-market performance vesting conditions. Non-market performance and service conditions are included in the assumptions about the number of options that are expected to vest.
The ultimate parent company measures the fair value using the Black-Scholes model. Where the amount is a capital contribution to the Company from Replimune Group, Inc., a corresponding entry is made to equity, as seen in the statement of changes in equity . Where the amount is a cost recharge to the Company from Replimune Group, Inc., a corresponding entry is made to amounts due to group undertakings.
Taxation
Income tax is recognised or provided at amounts expected to be recovered or paid using the tax rates and tax laws that have been enacted or substantively enacted at the year end date.
Current tax includes research and development tax credits, which are calculated in accordance with the UK research and development tax credit regime that is applicable to small and medium sized companies.
Deferred income tax is recognised on temporary differences arising between the tax bases of assets and liabilities and their carrying amounts in the financial statements.
Deferred income tax is determined using tax rates (and laws) that have been enacted or substantively enacted by the balance sheet date and are expected to apply when the related deferred income tax asset is realised or the deferred income tax liability is settled.
Deferred income tax assets are recognised only to the extent that it is probable that future taxable profit will be available against which the temporary differences can be utilised.
Current and deferred tax assets and liabilities are not discounted and no deferred income tax assets and liabilities are offset in these financial statements.
Foreign currency translation
Foreign currency transactions are translated into the functional currency using the exchange rates prevailing at the dates of the transactions or valuation where items are re-measured.
Foreign exchange gains and losses resulting from the settlement of such transactions and from the translation at period-end exchange rates of monetary assets and liabilities denominated in foreign currencies are recognised in the statement of comprehensive income. All other foreign exchange gains and losses are presented in the statement of profit or loss on a net basis, within "other gains/(losses)".
3 Material accounting policies (continued)
Leases
The lease liability is initially measured at the present value of the lease payments that are not paid at the commencement date, discounted using the interest rate implicit in the lease or, if that rate cannot be readily determined, the applicable incremental borrowing rate, which is the rate that, as a lessee, the Company would have to pay to borrow the funds necessary to obtain an asset of similar value in a similar economic environment with similar terms and conditions. Lease payments are allocated between principal and finance cost. The finance cost is charged to profit or loss over the lease period, so as to produce a constant periodic rate of interest on the remaining balance of the liability for each period.
The lease liability is subsequently measured at amortised cost using the effective interest method and is remeasured when there is a change in future lease payments or if the assessment of whether the Company will exercise a purchase, extension or termination option changes.
The policies adopted and the details of the effect of adopting the standard, are set out in note 16 to these financial statements.
Payments associated with short-term leases of equipment and all leases of low-value assets are recognised on a straight-line basis as an expense in profit or loss. Short-term leases are leases with a lease term of 12 months or less.
Measurement of lease liabilities
The majority of the Company's leases relate to property. A lease liability is recognised when the Company obtains control of the right-to use asset, that is the subject of the lease. Interest is charged to finance costs.
At inception, the Company evaluates whether is reasonably certain that any option to extend the lease will be exercised. Normally, where the initial term of a lease at inception is for at least five years, it would be unusual to consider such options at the inception of the lease. The Company will continue to monitor the likelihood of exercising such options throughout the initial lease term. When the Company is committed to extending the lease and where the lessor has consented to such an extension, the Company will consider the option to be reasonably certain to be exercised. In such circumstances, the right of use asset and the lease liabilities recognised are adjusted to reflect the extended term.
Research and development
Research and development costs are written off as incurred, as the technical and commercial feasibility of any resultant asset for sale or use has yet to be established.
Pensions
Contributions to defined contribution plans are expensed in the period to which they relate.
Consolidation
The Company is a wholly owned subsidiary of Replimune Group, Inc., and is included in the consolidated financial statements of Replimune Group, Inc., which are publicly available (see note 22). Consequently, the Company has taken advantage of the exemption from preparing consolidated financial statements under the terms of section 401 of the Companies Act 2006.
4 Critical accounting estimates and judgements
The Company makes estimates and judgements concerning the future. The resulting accounting estimates will, by definition, seldom equal the related actual results.
There are no estimates and assumptions that have a significant risk of causing a material adjustment to the carrying amounts of assets and liabilities within the next financial year.
5 Directors' emoluments 2026 2025
$ $
Director remunerated by the Company:
Salary - 203,636
- 203,636
The above represents the highest paid director who did not exercise any share options in the current or previous year. No directors accrued retirement benefits under the defined contribution pension scheme of the Company in the current or previous year. In the current year, no directors are remunerated by the Company (2025: 1). This is due to the individual no longer being a director of the Company.
For the year ended 31 March 2026, the directors were not remunerated by the Company. Costs were borne out of Replimune Group, Inc.
6 Staff costs 2026 2025
$ $
Wages and salaries 5,812,038 4,814,172
Equity-settled share-based payments (see note 19) 1,527,989 626,769
Social security costs 660,024 448,716
Other pension costs 802,633 640,938
8,802,684 6,530,595
Monthly average number of employees during 2026 2025
the financial year Number Number
Administration 2 2
Research and development 77 66
79 68
The Company employed 77 staff as at 31 March 2026 (2025: 74).
7 Other losses/(gains) 2026 2025
$ $
Exchange loss/(gain) on monetary assets 256,516 (343,563)
8 Operating loss 2026 2025
$ $
The operating loss is stated after charging/ (crediting):
Research and development expenditure (including staff costs but excluding recharges from the ultimate parent company) 12,345,461 10,270,230
Equity-settled share-based payments (note 19) 1,527,989 626,769
Services provided by the Company's auditors;
- fee payable for the audit 114,520 119,458
- fees payable for tax compliance and other services 56,859 72,223
Depreciation -excluding right of use asset (note 12) 541,745 709,618
Depreciation -right of use asset (note 12) 312,457 165,840
Intercompany charges -general and administrative expenses 24,298,577 18,056,506
Intercompany charges -research and development expenditure 207,473,856 184,540,246
Exchange loss/(gain) on monetary assets (note 7) 256,516 (343,563)
Intercompany charges represent costs recharged from the ultimate parent company, Replimune Group, Inc., to Replimune Limited, in respect of services where the costs are incurred by the ultimate parent but the company receives the service.
9 Finance income 2026 2025
$ $
Bank interest receivable 75,262 70,209
10 Finance costs 2026 2025
$ $
Interest expense on lease liability 248,767 279,833
11 Income tax 2026 2025
$ $
Analysis of income tax credit in year
Current tax:
UK corporation tax on losses for the financial year (1,604,188) (1,772,635)
Current income tax charge on profit on ordinary activities 1,604,188 1,772,635
Deferred tax - -
Total Income tax charge on profit on ordinary activities 1,604,188 1,772,635
Factors affecting tax credit for year
The differences between the tax assessed for the year and the standard rate of corporation tax in the UK are explained as follows:
2026 2025
$ $
Loss on ordinary activities before tax 249,278,562 216,465,950
Standard rate of corporation tax in the UK 25% 25%
Loss on ordinary activities multiplied by the standard rate of corporation tax in the UK 62,319,641 54,116,488
Effects of:
Expenses not deductible for tax purposes (544,567) (181,088)
Qualifying R&D expenditure (1,790,048) (1,910,765)
Qualifying R&D credit 2,136,096 2,292,918
Losses carried forward (61,756,258) (53,779,625)
Other (including currency retranslations) 1,239,324 1,234,707
Total income tax credit for the financial year 1,604,188 1,772,635
A deferred tax asset is not recognised within these financial statements on local currency losses of $986,980,593 (2025: $732,469,156) that remain unrelieved and carried forward. There is uncertainty as to whether there will be sufficient taxable profits in the future to offset this amount.
Similarly, a deferred tax liability of £Nil (2022: £Nil) is not provided for within these financial statements on capital allowances claimed in excess of the depreciation charges on the assets concerned.
Factors that may affect future tax charges
There are currently no new factors which may affect future tax charges.
12 Property, plant and equipment
Right of use asset: Property Fixtures, fittings, tools & equipment Total
$ $ $ $
Cost
At 1 April 2024 1,402,442 2,846,738 2,224,038 6,473,218
Additions in the previous year - - 303,252 303,252
Disposals in the previous year (83,174) - (24,243) (107,417)
At 31 March 2025 1,319,268 2,846,738 2,503,047 6,669,053
Additions in the current year - - 403,661 403,661
At 31 March 2026 1,319,268 2,846,738 2,906,708 7,072,714
Accumulated depreciation
At 1 April 2024 854,990 916,525 1,338,342 3,109,857
Charge for the previous year 359,086 165,840 350,532 875,458
On disposals (23,397) - (24,243) (47,640)
At 31 March 2025 1,190,679 1,082,365 1,664,631 3,937,675
Charge for the current year 77,081 312,457 464,664 854,202
At 31 March 2026 1,267,760 1,394,822 2,129,295 4,791,877
Carrying amount
At 31 March 2026 51,508 1,451,916 777,413 2,280,837
At 31 March 2025 128,589 1,764,373 838,416 2,731,378
13 Investment in subsidiary 2026 2025
$ $
Investment in Replimune (Ireland) Limited - -
Details of the subsidiary company , which has been dormant since incorporation , are as follows:
Name of the undertaking Address and country of incorporation or registration Proportion of nominal value of issued shares held by the Company
Replimune (Ireland) Limited 38 Upper Mount Street, Dublin 2, Dublin, Ireland 100%
14 Prepayments and other receivables 2026 2025
$ $
Amounts owed by group undertakings - 61,470
Other debtors 321,822 380,237
Prepayments 470,747 666,922
792,569 1,108,629
Amounts owed by group undertakings are unsecured, interest free, have no fixed date of repayment and are repayable on demand.
15 Current tax receivable 2026 2025
$ $
Tax credit receivable 3,360,927 3,724,980
16 Lease Liabilities
On 4 April 2016 the Company entered into a lease on the business premises in Abingdon, Oxon for a principal rent of £279,016 per annum with a break clause on the fifth anniversary. On 29 June 2020 the Company entered into a Deed of Variation to extend the lease on the premises to 3 April 2031 at the same annual rent. On 1 November 2021 the Company entered into a second lease for adjoining premises for a principal rent of £82,000 per annum for 5 years. On 31 March 2023 the Company entered into a third lease for adjoining premises for a principal rent of £72,000 per annum for 5 years.
The carrying value of the right of use assets included within property, plant and equipment as at 31 March 2026 is $1,451,916 (2025: $1,764,373). The following table summarises the future minimum lease payments under the Company`s lease liabilities:
2026 2025
$ $
Depreciation charge for the right of use assets: property (312,457) (165,840)
Additions to the right of use assets - -
Net book amount of right to use assets 1,451,916 1,764,373
Interest expense on lease liabilities (248,767) (279,833)
Cash outflow for leases – principal payments (433,286) (272,737)
Cash outflow for leases – interest payments (248,767) (279,833)
Analysis of lease liabilities: $ $
Present value of minimum lease payments due:
In one year or less 527,103 560,088
In more than one year but less than five years 1,022,508 938,868
In more than five years - 338,147
Present value of lease liabilities total 1,549,611 1,837,103
Current portion 527,103 560,088
Non-current portion 1,022,508 1,277,015
17 Trade and other payables 2026 2025
$ $
Trade creditors 640,728 631,139
Amounts owed to group undertakings 24,198,806 40,309,556
Other taxes and social security costs 262,050 208,561
Lease liability (see note 16) 527,103 560,088
Accruals and deferred income 2,534,532 1,915,311
28,163,219 43,624,655
All amounts included within trade and other payables are due within 12 months. Amounts owed to group undertakings are unsecured, interest free, have no fixed date of repayment and are repayable on demand.
18 Called up share capital
2026 2025 2026 2025
Number Number $ $
Allotted, called up and fully paid:
Ordinary shares 500,000 500,000 446 446
Seed Preferred 200,000 200,000 179 179
Series A Preferred 864,553 864,553 874 874
1,499 1,499
The nominal value of all share classes is $0.001 per share.
The Ordinary shares were allotted at par on incorporation. These shares rank behind the Series A shares in respect of dividends and behind the Series A and Seed Preferred shares on a liquidation event, but rank pari passu with all shares in all other respects.
The Seed Preferred shares rank behind the Series A shares in respect of dividends, behind Series A shares but ahead of Ordinary shares on a liquidation event, but rank pari passu with all shares in all other respects.
Series A Preferred shares rank ahead of the Ordinary and Seed Preferred shares in respect of dividends and on a liquidation event, but rank pari passu with all shares in all other respects.
All classes of share carry the right of 1 vote per share and do not confer a right of redemption. There is no rate set for dividends on preferred shares.
19 Share-based compensation
The US parent company, Replimune Group, Inc. issues equity settled share-based payments to certain employees. Options granted are non-transferable and lapse on cessation of employment. The directors determined that the exercise prices at the date of each grant were not less than the fair market value of the shares.
The 'Replimune Limited 2015 Enterprise Management Incentive Plan' was approved in February 2016, the 'Replimune Group, Inc. 2017 Equity Compensation Plan Nonqualified Stock Option Grant Agreement' was approved in July 2017, and the 'Replimune Group, Inc. 2018 Omnibus Incentive Compensation Plan Non-qualified Stock Option Grant Agreement' as well as the 2018 Omnibus Incentive Compensation Plan which provides for the grant of restricted stock units, were approved in July 2018.
Options become vested and exercisable as to 25% of the shares subject to the option on the 1st anniversary of grant and monthly vesting thereafter over the next 36 months. Options may not be exercised after the 10th anniversary of the grant date and if not exercised by that date shall lapse.
The vesting and exercisability of the options are cumulative, but shall not exceed 100% of the shares subject to the option.
2026 2025
Average Average
exercise price Number of exercise price Number of
Summary of Non-Qualified Share per option options per option options
options granted under the plan: $ No $ No
At 1 April 9.560 1,177,455 13.556 1,167,659
Granted during the year 8.407 102,556 8.436 106,461
Exercised/ released during year 13.562 (36,394) 5.488 (1,896)
Forfeited/ expired during year 2.457 (20,855) 19.474 (94,769)
At 31 March 12.422 1,222,762 9.560 1,177,455
Vested and exercisable 12.857 1,038,961 12.809 961,033
2026 2025
Average Average
exercise price Number of exercise price Number of
Summary of Restricted Stock Unit per option options per option options
options granted under the plan: $ No $ No
At 1 April 10.796 296,745 23.714 246,056
Awarded during the year 8.613 264,489 8.610 187,180
Exercised/ released during year 12.951 (76,056) 20.327 (61,287)
Forfeited during the year 9.367 (32,412) 17.572 (75,204)
At 31 March 9.261 452,766 10.796 296,745
Vested /released - - - 61,287
No Non-qualified or RSU share options in the 2 tables above expired during the year (2025: none).
19 Share-based compensation (continued)
Non-Qualified Share options outstanding at the end of the year have the following expiry dates and exercise prices:
Non-Qualified Share options 2026 2025
Grant date Expiry date Exercise price Share options Share options
$ No No
10-Mar-16 (EMI scheme) 10-Mar-26 1.75 - 16,215
12-Oct-16 (EMI scheme) 12-Oct-26 1.75 10,644 12,842
10-Mar-17 10-Mar-27 1.75 16,716 16,716
26-Jul-17 26-Jul-27 3.30 200,676 201,199
02-Aug-17 02-Aug-27 3.30 9,946 9,946
31-Jan-18 31-Jan-28 3.83 9,946 9,946
19-Jul-18 19-Jul-28 15.00 142,924 145,274
26-Sep-18 26-Sep-28 17.63 1,500 1,500
28-Nov-18 28-Nov-28 15.00 4,000 6,500
10-Dec-18 10-Dec-28 14.00 500 500
11-Feb-19 11-Feb-29 16.24 3,000 3,000
11-Mar-19 11-Mar-29 11.14 2,500 2,500
01-Apr-19 01-Apr-29 15.50 100,746 102,034
08-Apr-19 08-Apr-29 16.75 5,700 5,700
01-Jul-19 01-Jul-29 14.00 3,000 5,500
01-Apr-20 01-Apr-30 9.78 186,257 192,182
01-Mar-21 01-Mar-31 35.42 11,000 11,000
01-Apr-21 01-Apr-31 31.58 68,470 70,630
04-May-21 04-May-31 32.53 17,200 17,200
16-Aug-21 16-Aug-31 29.78 1,390 1,390
11-Oct-21 11-Oct-31 30.48 1,130 1,130
01-Apr-22 01-Apr-32 18.26 63,417 65,782
16-May-22 16-May-32 14.53 1,950 1,950
23-May-22 23-May-32 14.22 1,390 1,390
08-Aug-22 08-Aug-32 20.27 1,130 1,130
22-Aug-22 22-Aug-32 19.74 1,390 1,390
03-Oct-22 03-Oct-32 17.12 1,800 1,800
01-Nov-22 01-Nov-32 19.06 2,920 2,920
14-Nov-22 14-Nov-32 20.64 1,800 1,800
21-Nov-22 21-Nov-32 18.87 1,100 1,390
05-Dec-22 05-Dec-32 19.95 6,100 6,100
23-Jan-23 23-Jan-33 27.52 1,425 1,800
01-Apr-23 01-Apr-33 17.66 60,317 62,859
17-Apr-23 17-Apr-33 16.90 - 1,800
15-May-23 15-May-33 18.74 19,170 19,170
05-Jun-23 05-Jun-33 22.60 1,130 1,130
31-Jul-23 31-Jul-33 21.07 2,260 2,260
21-Aug-23 21-Aug-33 19.70 4,770 4,770
18-Sep-23 18-Sep-33 18.00 1,800 1,800
Subtotal c/fwd 971,114 1,014,145
19 Share-based compensation (continued)
Non-Qualified Share options 2026 2025
Grant date Expiry date Exercise price Share options Share options
$ No No
Subtotal b/fwd 971,114 1,014,145
25-Sep-23 25-Sep-33 16.15 460 460
09-Oct-23 09-Oct-33 15.32 1,390 1,390
16-Oct-23 16-Oct-33 14.65 5,550 5,550
23-Oct-23 23-Oct-33 13.65 2,920 2,920
20-Nov-23 20-Nov-33 10.18 1,130 1,130
02-Jan-24 02-Jan-34 8.67 52,291 52,291
01-Apr-24 01-Apr-34 7.73 72,263 76,824
24-Jun-24 24-Jun-34 8.76 3,165 3,165
05-Aug-24 05-Aug-34 9.72 2,990 2,990
19-Aug-24 19-Aug-34 10.28 1,825 1,825
03-Sep-24 03-Sep-34 10.28 - 3,165
15-Oct-24 15-Oct-34 10.54 1,690 1,690
28-Oct-24 28-Oct-34 12.05 1,690 1,690
05-Nov-24 05-Nov-34 12.02 2,945 2,945
06-Jan-25 06-Jan-35 12.02 1,120 1,120
05-Feb-25 05-Feb-35 14.25 2,945 2,945
05-Mar-25 05-Mar-35 12.29 1,210 1,210
01-Apr-25 01-Apr-35 8.40 84,944 -
07-Apr-25 07-Apr-35 7.49 3,320 -
05-May-25 05-May-35 10.01 1,825 -
05-Jun-25 05-Jun-35 9.75 3,285 -
05-Aug-25 05-Aug-35 6.32 1,120 -
16-Mar-26 16-Mar-36 7.36 1,570 -
Total 1,222,762 1,177,455
2026 2025
Non-Qualified Share options
Weighted average remaining contractual life of options outstanding at end of the year: 876 days 1,858 days
Weighted fair value in USD 1,118,100 2,001,831
19 Share-based compensation (continued)
Restricted Stock Unit options outstanding at the end of the year have the following expiry dates and exercise prices:
Restricted Stock Unit options 2026 2025
Grant date Expiry date Exercise price Share options Share options
$ No No
01-Apr-21 01-Apr-31 31.58 - 4,203
16-Aug-21 16-Aug-31 29.78 - 230
11-Oct-21 11-Oct-31 30.48 - 188
01-Apr-22 01-Apr-32 18.26 4,920 10,624
16-May-22 16-May-32 14.53 325 650
23-May-22 23-May-32 14.22 230 460
08-Aug-22 08-Aug-32 20.27 188 376
22-Aug-22 22-Aug-32 19.74 230 460
03-Oct-22 03-Oct-32 17.12 300 600
01-Nov-22 01-Nov-32 19.06 488 976
14-Nov-22 14-Nov-32 20.64 300 600
21-Nov-22 21-Nov-32 18.87 - 460
05-Dec-22 05-Dec-32 19.95 1,018 2,036
23-Jan-23 23-Jan-33 27.52 - 600
01-Apr-23 01-Apr-33 17.66 14,052 23,025
17-Apr-23 17-Apr-33 16.90 - 900
15-May-23 15-May-33 18.74 6,390 9,585
05-Jun-23 05-Jun-33 22.60 376 563
31-Jul-23 31-Jul-33 21.07 752 1,126
21-Aug-23 21-May-33 19.70 1,586 2,378
18-Sep-23 18-Sep-33 18.00 600 900
25-Sep-23 25-Sep-33 16.15 156 233
09-Oct-23 09-Oct-33 15.32 460 690
16-Oct-23 16-Oct-33 14.65 1,850 2,775
23-Oct-23 23-Oct-33 13.65 976 1,463
20-Nov-23 20-Nov-33 10.18 376 563
02-Jan-24 02-Jan-34 8.67 5,677 11,353
31-Jan-24 31-Jan-34 7.76 42,025 45,310
01-Apr-24 01-Apr-34 7.73 88,569 127,908
24-Jun-24 24-Jun-34 8.76 4,755 6,340
05-Aug-24 05-Aug-34 9.72 4,475 5,965
19-Aug-24 19-Aug-34 10.28 2,742 3,655
03-Sep-24 03-Sep-34 10.28 - 6,340
15-Oct-24 15-Oct-34 10.54 2,528 3,370
28-Oct-24 28-Oct-34 12.05 2,528 3,370
05-Nov-24 05-Nov-34 12.02 4,422 5,895
06-Jan-25 06-Jan-35 12.02 1,684 2,245
05-Feb-25 05-Feb-35 14.25 4,422 5,895
Subtotal c/fwd 199,400 294,310
19 Share-based compensation (continued)
Restricted Stock Unit options 2026 2025
Grant date Expiry date Exercise price Share options Share options
$ No No
Subtotal b/fwd 199,400 294,310
05-Mar-25 05-Mar-35 12.29 1,827 2,435
01-Apr-25 01-Apr-35 8.40 193,874 -
07-Apr-25 07-Apr-35 7.49 6,660 -
05-May-25 05-May-35 10.01 3,650 -
05-Jun-25 05-Jun-35 9.75 6,600 -
05-Aug-25 05-Aug-35 6.32 2,245 -
15-Dec-25 15-Dec-35 9.95 35,375 -
16-Mar-26 16-Mar-36 7.36 3,135 -
452,766 296,745
Weighted average remaining contractual life of options outstanding at end of the year: 796 days 3,201 days
Weighted fair value in USD 3,463,660 2,893,264
The assessed fair value at grant date of options granted during the year ended 31 March 2026 was $5.86 per option (2025: $9.75). The fair value at grant date is independently determined using an adjusted form of the Black-Scholes model that takes into account the exercise price, the term of the option, the impact of dilution (where material), the share price at grant date and expected price volatility of the underlying share, the expected dividend yield, the risk-free interest rate for the term of the option, and the correlations and volatilities of the peer group companies.
Other model inputs for options granted on each date during the year included:
[a] share prices: $6.32 to $10.01 (2025: $5.18 to $14.25).
[b] exercise prices: $6.32 to $10.01 (2025: $5.18 to $14.25).
[c] expected life in years: 6.08 (2025: 6.08).
[d] expected annualised volatility: 77.15% (2025: 76.32%).
[e] expected dividend yield 0% (2025: 0%).
[f] discount rate - bond equivalent yield: 3.971 (2025: 4.275).
The expected price volatility is based on the historic volatility (based on the remaining life of the options), adjusted for any expected changes to future volatility.
2026 2025
$ $
Total expense arising from share-based payment transactions 1,527,989 626,769
20 Financial instruments
The Company has no financial assets or liabilities measured at fair value through profit or loss.
Financial instruments by category 2026 2025
$ $
Financial assets at amortised cost:
Other debtors 321,822 441,707
Cash and cash equivalents 4,439,720 2,393,424
Financial liabilities at amortised cost:
Trade and other payables (28,163,219) (43,624,655)
Non-current lease liabilities (1,022,508) (1,277,015)
Included in trade and other payables is a current lease liability of $527,103 (2025: $560,088). The contractual maturity of the financial liabilities are reflected within the notes of the financial statements. The contractual maturity of lease liabilities is included within note 16 and trade and other payables in note 17. Prepayments have been excluded from financial assets as they are not considered to be a financial instrument.
None of the above financial assets are impaired or past due and they are considered to be of good credit quality. The credit risk for cash and cash equivalents is considered negligible, since the main counterparty is a reputable bank with a high quality external credit rating. Foreign currency risk is considered negligible as insignificant funds are held in amounts other than the functional currency.
21 Related party transactions
Key management compensation
The key management personnel have been determined to be the directors and no other staff. Therefore key management compensation is as disclosed in note 5.
Parent undertaking
The Company received a capital contribution of $264,883,183 (2025: $256,424,182) from Replimune Group, Inc. during the year.
The Company was recharged $24,298,577 (2025: $18,056,506) included in administrative expenses and $207,473,856 (2025: $184,540,246) included in research and development expenditure, from Replimune Group, Inc., during the year.
The Company owed $24,198,806 (2025: $40,309,556), to Replimune Group, Inc. at the end of the year.
22 Controlling party
The ultimate controlling party and ultimate parent is Replimune Group,Inc., a company incorporated in the United States of America which owns 100% of the share capital of the Company, and is both the largest and smallest group of undertakings to consolidate these financial statements. The consolidated financial statements of Replimune Group, Inc. are available from 69 Innovation Drive, Milton Park, Abingdon, Oxfordshire, OX14 4RQ, United Kingdom.
The directors consider there to be no single controlling party of Replimune Group, Inc.
23 Post Balance sheet events
On 10 April 2026 the Group received a CRL (Complete Response Letter) from the FDA for the BLA for RP1 in combination with nivolumab for the treatment of advanced melanoma. As a result of the CRL, the Group announced its plan for a restructuring, which included a reduction of its workforce by approximately 55%. As a result of this reduction in force, the Group estimates that it will record a charge in the range of $9.8 million to $10.3 million during the three months ended June 30, 2026, related to employee termination benefits, including severance, all of which is anticipated to result in cash expenditures. Communication has been made to all impacted employees under this restructuring plan. The Group expects the reduction in force to be substantially complete by the end of the first quarter of fiscal 2027.
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