Company registration number 04336899 (England and Wales)
DOMAINEX LIMITED
ANNUAL REPORT AND FINANCIAL STATEMENTS
FOR THE YEAR ENDED 31 DECEMBER 2025
Whitings LLP
Chartered Accountants
Greenwood House
Greenwood Court
Skyliner Way
Bury St Edmunds
Suffolk
IP32 7GY
DOMAINEX LIMITED
COMPANY INFORMATION
Directors
Mr T E Beckett
Mr F S Bury
Dr H P French
(Appointed 30 April 2025)
Mr R S Harris
Dr J M Hills
Dr E Littler
Prof. L Pearl
Company number
04336899
Registered office
Chesterford Research Park
Little Chesterford
Saffron Walden
Essex
CB10 1XL
Auditor
Whitings LLP
Chartered Accountants & Statutory Auditor
Greenwood House
Greenwood Court
Skyliner Way
Bury St Edmunds
Suffolk
IP32 7GY
Bankers
Barclays Bank PLC
Cambridge Benet Street Branch
Cambridge
Cambridgeshire
CB2 3AA
DOMAINEX LIMITED
CONTENTS
Page
Strategic report
1 - 2
Directors' report
3 - 4
Independent auditor's report
5 - 7
Statement of comprehensive income
8
Balance sheet
9
Statement of changes in equity
10
Statement of cash flows
11
Notes to the financial statements
12 - 28
DOMAINEX LIMITED
STRATEGIC REPORT
FOR THE YEAR ENDED 31 DECEMBER 2025
- 1 -
The directors present the strategic report for the year ended 31 December 2025.
Principal activities
Domainex provides drug discovery services to pharmaceutical, biotechnology and academic clients worldwide, offering chemistry and biology solutions that support medicine pipelines across many human diseases.
Business Review
2025 was challenging for CROs and Domainex was affected by the loss of its major synthetic chemistry client, contributing to a 5% turnover decline to approximately £10.45m from £11.04m in 2024. Gross margin improved to 46.98% (42.42% last year), and the operating loss reduced to £0.662m from £1.35m, helped by sub‑letting space at Unity but still impacted by the cost of operating both Chesterford and Unity sites. The reported EBITDA for the year is £0.35m an increase of £0.64m from the previous year. Cash management remained a priority, with tight control of receivables, stock and capital expenditure, while investment continued in biology and bioanalytical capabilities at the Sigma Building on Unity Campus. Domainex’s strong client relationships, differentiated technologies, and strengths in computational chemistry, structural biology, and biophysics, along with its Direct‑to‑Biology platform, helped maintain key accounts in a competitive market.
Future Developments
A strategic review confirmed that Domainex will pivot toward higher‑value, differentiated services where it can demonstrate leadership and secure premium pricing. The strategy rests on three elements: closing the Chesterford chemistry facility at lease expiry in November 2026; refocusing services toward computational and biology‑led Direct‑to‑Biology workflows and away from commoditised routine chemistry; and raising £1.0–1.5m of new equity to fund restructuring and growth. Chesterford’s closure is expected to significantly reduce property overheads, consolidate scientific teams, release capital and management attention, and support a lower fixed‑cost base, with pro forma 2026 forecasts indicating positive profit before tax and EBITDA above £1m once Chesterford overheads are excluded. Equity proceeds will fund restructuring and closure costs, a 25% uplift in 2026 sales and marketing spend versus 2025, website redevelopment, extra business development hires through 2027–2028, and continued investment in computational infrastructure and biology platforms. From 2027, Domainex expects to generate sustainable profits by acting as a strategic discovery partner, using advanced modelling and Direct‑to‑Biology workflows to accelerate early decisions, improve productivity, and deliver higher‑margin, high‑impact services.
Principal risks and uncertainties
Macroeconomic and funding uncertainty for biotech clients continues to affect project timing and size, though Domainex benefits from its reputation, Cambridge location, experienced staff, milestone track record and diverse client base, as well as rising R&D outsourcing. Competitive risks stem from UK peers and lower‑cost offshore providers, particularly for commoditised chemistry, but are mitigated by Domainex’s focus on IP‑rich work, strong technology platforms, integrated services and high barriers to matching its capabilities. Restructuring and the Chesterford closure bring execution risks around client disruption, staff retention, and cost overruns, which are being managed through phased consolidation, expert planning, transparent client communication, strong project management, and backing from the equity raise. Cash and liquidity pressures in 2026 from redundancy, closure costs, lower transition revenue and investment are being addressed via the planned equity raise, strict cost control, careful working capital management and prudent capital expenditure. Consolidation to a single site is expected to simplify business continuity, supported by existing continuity and disaster recovery processes that are periodically reviewed. Staff retention remains a key focus, with regular reviews, development plans, internal promotions, clear career paths, a collegiate working environment, CSR support, employee forums, competitive benefits, and active retention monitoring, with additional measures for critical roles. Domainex also supports future talent through internships, apprenticeships and schoolwork‑experience opportunities.
DOMAINEX LIMITED
STRATEGIC REPORT (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
- 2 -
Key performance indicators
Key financial KPIs are recognised revenue, gross margins, operating profit or loss, EBITDA, cash generation and balances, and project‑level profitability. Given the restructuring, 2026 will be particularly focused on overhead reduction versus pro forma targets, revenue mix shifting toward higher‑value services, margins on biology and computational work, and cash usage and adequacy through the transition.
Other KPIs include employee retention (especially for critical roles), client retention and satisfaction, client mix, rate of new client acquisition in target areas, contract renewals and extensions, health and safety performance, and departmental capacity utilisation, especially in biology post‑consolidation.
Conclusion
2025 was difficult, ending with the loss of a major synthetic chemistry client, but the Board has acted with a clear plan to reshape Domainex around computational design, Direct‑to‑Biology workflows and integrated biology services. The Chesterford closure and reduction in commodity chemistry, combined with focused investment in differentiated capabilities and commercial resources, are expected to restore profitability and support sustainable growth from 2027 onwards. With a strong scientific team, proven delivery, proprietary platforms and a focus on high‑value services, Domainex aims to emerge from this transition as a stronger, more focused and more profitable business.
Dr E Littler
Director
10 April 2026
DOMAINEX LIMITED
DIRECTORS' REPORT
FOR THE YEAR ENDED 31 DECEMBER 2025
- 3 -
The directors present their annual report and financial statements for the year ended 31 December 2025.
Results and dividends
The results for the year are set out on page 8.
The loss for the year, after taxation, amounted to £565,042 (2024 - £1,047,147).
No dividends have been paid or proposed (2024 - £Nil).
Directors
The directors who held office during the year and up to the date of signature of the financial statements were as follows:
Mr B K Knight
(Resigned 31 July 2025)
Mr T E Beckett
Mr F S Bury
Dr H P French
(Appointed 30 April 2025)
Mr R S Harris
Dr J M Hills
Dr E Littler
Prof. L Pearl
Post reporting date events
The board met on the 18th of March and confirmed applications had been received from over 75% of shareholders for subscriptions for a new share issue. At time of the approving these accounts the company has received applications for over £1 million in new Equity which will result in the issue of over 67,000 new D Preference Shares.
Future developments
Future developments are included in the Strategic Report.
Statement of directors' responsibilities
The directors are responsible for preparing the strategic report, the annual report and the financial statements in accordance with applicable law and regulations.
Company law requires the directors to prepare financial statements for each financial year. Under that law the directors have elected to prepare the financial statements in accordance with United Kingdom Generally Accepted Accounting Practice (United Kingdom Accounting Standards and applicable law). Under company law, the directors must not approve the financial statements unless they are satisfied that they give a true and fair view of the state of affairs of the company and of the profit or loss of the company for that period.
In preparing these financial statements, the directors are required to:
select suitable accounting policies and then apply them consistently;
make judgements and accounting estimates that are reasonable and prudent; and
prepare the financial statements on the going concern basis unless it is inappropriate to presume that the company will continue in business.
The directors are responsible for keeping adequate accounting records that are sufficient to show and explain the company’s transactions and disclose with reasonable accuracy at any time the financial position of the company and enable them to ensure that the financial statements comply with the Companies Act 2006. They are also responsible for safeguarding the assets of the company and hence for taking reasonable steps for the prevention and detection of fraud and other irregularities.
DOMAINEX LIMITED
DIRECTORS' REPORT (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
- 4 -
Statement of disclosure to auditor
So far as each person who was a director at the date of approving this report is aware, there is no relevant audit information of which the company’s auditor is unaware. Additionally, the directors individually have taken all the necessary steps that they ought to have taken as directors in order to make themselves aware of all relevant audit information and to establish that the company’s auditor is aware of that information.
On behalf of the board
Dr E Littler
Director
10 April 2026
DOMAINEX LIMITED
INDEPENDENT AUDITOR'S REPORT
TO THE MEMBERS OF DOMAINEX LIMITED
- 5 -
Opinion
We have audited the financial statements of Domainex Limited (the 'company') for the year ended 31 December 2025 which comprise the statement of comprehensive income, the balance sheet, the statement of changes in equity, the statement of cash flows and notes to the financial statements, including significant accounting policies. The financial reporting framework that has been applied in their preparation is applicable law and United Kingdom Accounting Standards, including Financial Reporting Standard 102 The Financial Reporting Standard applicable in the UK and Republic of Ireland (United Kingdom Generally Accepted Accounting Practice).
In our opinion the financial statements:
give a true and fair view of the state of the company's affairs as at 31 December 2025 and of its loss for the year then ended;
have been properly prepared in accordance with United Kingdom Generally Accepted Accounting Practice; and
have been prepared in accordance with the requirements of the Companies Act 2006.
We conducted our audit in accordance with International Standards on Auditing (UK) (ISAs (UK)) and applicable law. Our responsibilities under those standards are further described in the Auditor's responsibilities for the audit of the financial statements section of our report. We are independent of the company in accordance with the ethical requirements that are relevant to our audit of the financial statements in the UK, including the FRC’s Ethical Standard, and we have fulfilled our other ethical responsibilities in accordance with these requirements. We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis for our opinion.
Conclusions relating to going concern
In auditing the financial statements, we have concluded that the directors' use of the going concern basis of accounting in the preparation of the financial statements is appropriate.
Based on the work we have performed, we have not identified any material uncertainties relating to events or conditions that, individually or collectively, may cast significant doubt on the company's ability to continue as a going concern for a period of at least twelve months from when the financial statements are authorised for issue.
Our responsibilities and the responsibilities of the directors with respect to going concern are described in the relevant sections of this report.
The other information comprises the information included in the annual report other than the financial statements and our auditor's report thereon. The directors are responsible for the other information contained within the annual report. Our opinion on the financial statements does not cover the other information and, except to the extent otherwise explicitly stated in our report, we do not express any form of assurance conclusion thereon. Our responsibility is to read the other information and, in doing so, consider whether the other information is materially inconsistent with the financial statements or our knowledge obtained in the course of the audit, or otherwise appears to be materially misstated. If we identify such material inconsistencies or apparent material misstatements, we are required to determine whether this gives rise to a material misstatement in the financial statements themselves. If, based on the work we have performed, we conclude that there is a material misstatement of this other information, we are required to report that fact.
We have nothing to report in this regard.
Opinions on other matters prescribed by the Companies Act 2006
In our opinion, based on the work undertaken in the course of our audit:
the information given in the strategic report and the directors' report for the financial year for which the financial statements are prepared is consistent with the financial statements; and
the strategic report and the directors' report have been prepared in accordance with applicable legal requirements.
DOMAINEX LIMITED
INDEPENDENT AUDITOR'S REPORT
TO THE MEMBERS OF DOMAINEX LIMITED (CONTINUED)
- 6 -
Matters on which we are required to report by exception
In the light of the knowledge and understanding of the company and its environment obtained in the course of the audit, we have not identified material misstatements in the strategic report or the directors' report.
We have nothing to report in respect of the following matters in relation to which the Companies Act 2006 requires us to report to you if, in our opinion:
adequate accounting records have not been kept, or returns adequate for our audit have not been received from branches not visited by us; or
the financial statements are not in agreement with the accounting records and returns; or
certain disclosures of directors' remuneration specified by law are not made; or
we have not received all the information and explanations we require for our audit.
Responsibilities of directors
As explained more fully in the directors' responsibilities statement, the directors are responsible for the preparation of the financial statements and for being satisfied that they give a true and fair view, and for such internal control as the directors determine is necessary to enable the preparation of financial statements that are free from material misstatement, whether due to fraud or error. In preparing the financial statements, the directors are responsible for assessing the company's ability to continue as a going concern, disclosing, as applicable, matters related to going concern and using the going concern basis of accounting unless the directors either intend to liquidate the company or to cease operations, or have no realistic alternative but to do so.
Auditor's responsibilities for the audit of the financial statements
Our objectives are to obtain reasonable assurance about whether the financial statements as a whole are free from material misstatement, whether due to fraud or error, and to issue an auditor's report that includes our opinion. Reasonable assurance is a high level of assurance but is not a guarantee that an audit conducted in accordance with ISAs (UK) will always detect a material misstatement when it exists. Misstatements can arise from fraud or error and are considered material if, individually or in the aggregate, they could reasonably be expected to influence the economic decisions of users taken on the basis of these financial statements.
Irregularities, including fraud, are instances of non-compliance with laws and regulations. We design procedures in line with our responsibilities, outlined above, to detect material misstatements in respect of irregularities, including fraud. The extent to which our procedures are capable of detecting irregularities, including fraud is detailed below.
Enquiry of management about any known or suspected instances of non-compliance with laws and regulations, accidents in the workplace, and fraud;
Enquiry of management around actual and potential litigation and claims;
Reviewing financial statement disclosures and testing to supporting documentation to assess compliance with applicable laws and regulations;
Challenging assumptions and judgements made by management in their significant accounting estimates, such as useful economic lives of tangible assets; and
Performing audit work over the risk of management override of controls, including testing of journal entries and other adjustments for appropriateness, and evaluating the business rationale of significant transactions outside the course of normal business.
Because of the inherent limitations of an audit, there is a risk that we will not detect all irregularities, including those leading to a material misstatement in the financial statements or non-compliance with regulation. This risk increases the more that compliance with a law or regulation is removed from the events and transactions reflected in the financial statements, as we will be less likely to become aware of instances of non-compliance. The risk is also greater regarding irregularities occurring due to fraud rather than error, as fraud involves intentional concealment, forgery, collusion, omission or misrepresentation.
A further description of our responsibilities is available on the Financial Reporting Council’s website at: https://www.frc.org.uk/auditorsresponsibilities. This description forms part of our auditor's report.
DOMAINEX LIMITED
INDEPENDENT AUDITOR'S REPORT
TO THE MEMBERS OF DOMAINEX LIMITED (CONTINUED)
- 7 -
This report is made solely to the company's members, as a body, in accordance with Chapter 3 of Part 16 of the Companies Act 2006. Our audit work has been undertaken so that we might state to the company's members those matters we are required to state to them in an auditor's report and for no other purpose. To the fullest extent permitted by law, we do not accept or assume responsibility to anyone other than the company and the company's members as a body, for our audit work, for this report, or for the opinions we have formed.
Jonathan Moore ACCA (Senior Statutory Auditor)
For and on behalf of Whitings LLP, Statutory Auditor
Chartered Accountants
Greenwood House
Greenwood Court
Skyliner Way
Bury St Edmunds
Suffolk
IP32 7GY
14 April 2026
DOMAINEX LIMITED
STATEMENT OF COMPREHENSIVE INCOME
FOR THE YEAR ENDED 31 DECEMBER 2025
- 8 -
2025
2024
Notes
£
£
Turnover
3
10,451,118
11,037,189
Cost of sales
(5,540,868)
(6,354,808)
Gross profit
4,910,250
4,682,381
Administrative expenses
(6,658,830)
(7,169,326)
Other operating income
3
1,086,482
1,141,639
Operating loss
4
(662,098)
(1,345,306)
Interest receivable and similar income
7
7,099
16,150
Interest payable and similar expenses
8
(57,073)
(62,416)
Loss before taxation
(712,072)
(1,391,572)
Tax on loss
9
147,030
344,425
Loss for the financial year
(565,042)
(1,047,147)
There are no recognised gains and losses for 2025 or 2024 other than those passing through the statement of comprehensive income.
There was no other comprehensive income for 2025 (2024 - £nil).
The notes on pages 12 to 28 form part of these financial statements.
DOMAINEX LIMITED
BALANCE SHEET
AS AT 31 DECEMBER 2025
31 December 2025
- 9 -
2025
2024
Notes
£
£
£
£
Fixed assets
Tangible assets
10
3,417,324
4,293,620
Investments
11
1,000
1,000
3,418,324
4,294,620
Current assets
Stocks
13
215,472
192,499
Debtors falling due after more than one year
14
1,189,064
1,020,297
Debtors falling due within one year
14
3,352,509
3,273,794
Cash at bank and in hand
458,368
973,530
5,215,413
5,460,120
Creditors: amounts falling due within one year
15
(2,834,430)
(3,029,481)
Net current assets
2,380,983
2,430,639
Total assets less current liabilities
5,799,307
6,725,259
Creditors: amounts falling due after more than one year
16
(92,033)
(273,234)
Provisions for liabilities
Deferred tax liability
18
104,992
289,819
(104,992)
(289,819)
Net assets
5,602,282
6,162,206
Capital and reserves
Called up share capital
21
5,648
5,641
Share premium account
22
1,614,158
1,612,275
Profit and loss reserves
22
3,982,476
4,544,290
Total equity
5,602,282
6,162,206
The notes on pages 12 to 28 form part of these financial statements.
The financial statements were approved by the board of directors and authorised for issue on 10 April 2026 and are signed on its behalf by:
Dr E Littler
Director
Company registration number 04336899 (England and Wales)
DOMAINEX LIMITED
STATEMENT OF CHANGES IN EQUITY
FOR THE YEAR ENDED 31 DECEMBER 2025
- 10 -
Share capital
Share premium account
Profit and loss reserves
Total
Notes
£
£
£
£
Balance at 1 January 2024
5,612
1,605,103
5,586,989
7,197,704
Year ended 31 December 2024:
Loss and total comprehensive income
-
-
(1,047,147)
(1,047,147)
Issue of share capital
21
29
7,172
-
7,201
Share based payments
-
-
4,448
4,448
Balance at 31 December 2024
5,641
1,612,275
4,544,290
6,162,206
Year ended 31 December 2025:
Loss and total comprehensive income
-
-
(565,042)
(565,042)
Issue of share capital
21
7
1,883
-
1,890
Share based payments
-
-
3,228
3,228
Balance at 31 December 2025
5,648
1,614,158
3,982,476
5,602,282
The notes on pages 12 to 28 form part of these financial statements.
DOMAINEX LIMITED
STATEMENT OF CASH FLOWS
FOR THE YEAR ENDED 31 DECEMBER 2025
- 11 -
2025
2024
Notes
£
£
£
£
Cash flows from operating activities
Cash absorbed by operations
25
(654,819)
(1,177,077)
Corporation tax received
-
783,634
Net cash outflow from operating activities
(654,819)
(393,443)
Investing activities
Purchase of tangible fixed assets
(79,133)
(862,186)
Proceeds from disposal of tangible fixed assets
14,501
Interest received
7,099
16,150
Net cash used in investing activities
(57,533)
(846,036)
Financing activities
Proceeds from issue of shares
1,890
7,201
Proceeds from new borrowing
611,800
Payment of finance leases obligations
(359,427)
(354,029)
Interest paid
(57,073)
(62,416)
Net cash generated from/(used in) financing activities
197,190
(409,244)
Net decrease in cash and cash equivalents
(515,162)
(1,648,723)
Cash and cash equivalents at beginning of year
973,530
2,622,253
Cash and cash equivalents at end of year
458,368
973,530
The notes on pages 12 to 28 form part of these financial statements.
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 31 DECEMBER 2025
- 12 -
1
Accounting policies
Company information
Domainex Limited is a private company limited by shares and is incorporated in England. The address of its registered office is Chesterford Research Park, Little Chesterford, Saffron Walden, Essex, CB10 1XL, near Cambridge.
1.1
Basis of preparation
These financial statements have been prepared in accordance with FRS 102 “The Financial Reporting Standard applicable in the UK and Republic of Ireland” (“FRS 102”) and the requirements of the Companies Act 2006.
The company is not required to prepare consolidated financial statements as all of its subsidiaries are permitted to be excluded from consolidation by section 405 and section 402 of the Companies Act 2006
1.2
Going concern
The directors have assessed the Company's ability to continue as a going concern, taking into account all available information about the future including the Company's current financial position, the ongoing support of its workforce, principal risks and uncertainties, current and anticipated trading performance, and its capital and liquidity requirements. In making this assessment, the directors have considered cash flow forecasts and budgets for a period of at least twelve months from the date of approval of these financial statements, together with the availability of existing financing facilities and the Company's ability to meet its obligations as they fall due. In particular the directors note that following the year end the company's shareholders agreed to a new Subscription and Open Offer to raise in excess of £1 million of additional equity funding for the company. On the basis of this assessment, the directors have a reasonable expectation that the Company has adequate resources to continue in operational existence for the foreseeable future. Accordingly, the financial statements have been prepared on the going concern basis.
1.3
Revenue
Revenue comprises sales of goods or services provided to customers net of value added tax and other sales taxes, less an appropriate deduction for actual and expected returns and discounts. Revenue is recognised when performance obligations are satisfied and the control of goods or services is transferred to the buyer. Where the performance obligation is satisfied over time, revenue is recognised in accordance with its progress towards complete satisfaction of that performance obligation.
Sale of goods
Turnover from the sale of goods is recognised when all of the following conditions are satisfied:
the Company has transferred the significant risks and rewards of ownership to the buyer;
the Company retains neither continuing managerial involvement to the degree usually associated with ownership nor effective control over the goods sold;
the amount of turnover can be measured reliably;
it is probable that the Company will receive the consideration due under the transaction; and
the costs incurred or to be incurred in respect of the transaction can be measured reliably.
Rendering of services
Turnover from a contract to provide services is recognised in the period in which the services are provided in accordance with the stage of completion of the contract when all of the following conditions are satisfied:
the amount of turnover can be measured reliably;
it is probable that the Company will receive the consideration due under the contract;
the stage of completion of the contract at the end of the reporting period can be measured reliably; and
the costs incurred and the costs to complete the contract can be measured reliably.
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
1
Accounting policies
(Continued)
- 13 -
Turnover from licence fees, contingent on the occurrence of a future event, is recognised only when it is probable that the fee will be received.
1.4
Intangible fixed assets
Intangible assets acquired separately from a business are recognised at cost and are subsequently measured at cost less accumulated amortisation and accumulated impairment losses.
Intangible assets acquired on business combinations are recognised separately from goodwill at the acquisition date where it is probable that the expected future economic benefits that are attributable to the asset will flow to the entity and the fair value of the asset can be measured reliably; the intangible asset arises from contractual or other legal rights; and the intangible asset is separable from the entity.
Amortisation is recognised so as to write off the cost or valuation of assets less their residual values over their useful lives on the following bases:
Patents & licences
20 % straight line
Goodwill
20 % straight line
1.5
Tangible fixed assets
Tangible fixed assets under the cost model are stated at historical cost less accumulated depreciation and any accumulated impairment losses. Historical cost includes expenditure that is directly attributable to bringing the asset to the location and condition necessary for it to be capable of operating in the manner intended by management.
At each reporting date the Company assesses whether there is any indication of impairment. If such indication exists, the recoverable amount of the asset is calculated as the higher of its fair value less costs to sell and its value in use. An impairment loss is recognised where the carrying amount exceeds the recoverable amount.
Depreciation is recognised so as to write off the cost or valuation of assets less their residual values over their useful lives on the following bases:
Short-term leasehold improvements
Ten years or the remaining life of the lease, if less, straight line
Plant and machinery
4-8 years straight line
Fixtures and fittings
4 years straight line
Office equipment
4-5 years straight line
The gain or loss arising on the disposal of an asset is determined as the difference between the sale proceeds and the carrying value of the asset, and is credited or charged to profit or loss.
1.6
Stocks
Stocks are stated at the lower of cost and estimated selling price less costs to complete and sell. Cost comprises direct materials and, where applicable, direct labour costs and those overheads that have been incurred in bringing the stocks to their present location and condition.
At each reporting date, an assessment is made for impairment. Any excess of the carrying amount of stocks over its estimated selling price less costs to complete and sell is recognised as an impairment loss in profit or loss. Reversals of impairment losses are also recognised in profit or loss.
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
1
Accounting policies
(Continued)
- 14 -
1.7
Cash and cash equivalents
Cash is represented by cash in hand and deposits with financial institutions repayable without penalty on notice of not more than 24 hours. Cash equivalents are highly liquid investments that mature in no more than three months from the date of acquisition and that are readily convertible to known amounts of cash with insignificant risk of change in value.
In the Statement of cash flows, cash and cash equivalents are shown net of bank overdrafts that are repayable on demand and form an integral part of the Company's cash management.
1.8
Financial instruments
The company has elected to apply the provisions of Section 11 ‘Basic Financial Instruments’ and Section 12 ‘Other Financial Instruments Issues’ of FRS 102 to all of its financial instruments.
Financial instruments are recognised in the company's balance sheet when the company becomes party to the contractual provisions of the instrument.
Financial assets and liabilities are offset, with the net amounts presented in the financial statements, when there is a legally enforceable right to set off the recognised amounts and there is an intention to settle on a net basis or to realise the asset and settle the liability simultaneously.
Basic financial assets
Basic financial assets, which include debtors and cash and bank balances, are initially measured at transaction price including transaction costs and are subsequently carried at amortised cost using the effective interest method unless the arrangement constitutes a financing transaction, where the transaction is measured at the present value of the future receipts discounted at a market rate of interest. Financial assets classified as receivable within one year are not amortised.
Other financial assets
Other financial assets, including investments in equity instruments which are not subsidiaries, associates or joint ventures, are initially measured at fair value, which is normally the transaction price. Such assets are subsequently carried at fair value and the changes in fair value are recognised in profit or loss, except that investments in equity instruments that are not publicly traded and whose fair values cannot be measured reliably are measured at cost less impairment.
Impairment of financial assets
Financial assets, other than those held at fair value through profit and loss, are assessed for indicators of impairment at each reporting end date.
Financial assets are impaired where there is objective evidence that, as a result of one or more events that occurred after the initial recognition of the financial asset, the estimated future cash flows have been affected. If an asset is impaired, the impairment loss is the difference between the carrying amount and the present value of the estimated cash flows discounted at the asset’s original effective interest rate. The impairment loss is recognised in profit or loss.
If there is a decrease in the impairment loss arising from an event occurring after the impairment was recognised, the impairment is reversed. The reversal is such that the current carrying amount does not exceed what the carrying amount would have been, had the impairment not previously been recognised. The impairment reversal is recognised in profit or loss.
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
1
Accounting policies
(Continued)
- 15 -
Derecognition of financial assets
Financial assets are derecognised only when the contractual rights to the cash flows from the asset expire or are settled, or when the company transfers the financial asset and substantially all the risks and rewards of ownership to another entity, or if some significant risks and rewards of ownership are retained but control of the asset has transferred to another party that is able to sell the asset in its entirety to an unrelated third party.
Classification of financial liabilities
Financial liabilities and equity instruments are classified according to the substance of the contractual arrangements entered into. An equity instrument is any contract that evidences a residual interest in the assets of the company after deducting all of its liabilities.
Basic financial liabilities
Basic financial liabilities, including creditors, bank loans, loans from fellow group companies and preference shares that are classified as debt, are initially recognised at transaction price unless the arrangement constitutes a financing transaction, where the debt instrument is measured at the present value of the future payments discounted at a market rate of interest. Financial liabilities classified as payable within one year are not amortised.
Debt instruments are subsequently carried at amortised cost, using the effective interest rate method.
Trade creditors are obligations to pay for goods or services that have been acquired in the ordinary course of business from suppliers. Amounts payable are classified as current liabilities if payment is due within one year or less. If not, they are presented as non-current liabilities. Trade creditors are recognised initially at transaction price and subsequently measured at amortised cost using the effective interest method.
Other financial liabilities
Derivatives, including interest rate swaps and forward foreign exchange contracts, are not basic financial instruments. Derivatives are initially recognised at fair value on the date a derivative contract is entered into and are subsequently re-measured at their fair value. Changes in the fair value of derivatives are recognised in profit or loss in finance costs or finance income as appropriate, unless hedge accounting is applied and the hedge is a cash flow hedge.
Debt instruments that do not meet the conditions in FRS 102 paragraph 11.9 are subsequently measured at fair value through profit or loss. Debt instruments may be designated as being measured at fair value through profit or loss to eliminate or reduce an accounting mismatch or if the instruments are measured and their performance evaluated on a fair value basis in accordance with a documented risk management or investment strategy.
Derecognition of financial liabilities
Financial liabilities are derecognised when the company’s contractual obligations expire or are discharged or cancelled.
1.9
Taxation
The tax expense represents the sum of the tax currently payable and deferred tax.
Current tax
The tax currently payable is based on taxable profit for the year. Taxable profit differs from net profit as reported in the profit and loss account because it excludes items of income or expense that are taxable or deductible in other years and it further excludes items that are never taxable or deductible. The company’s liability for current tax is calculated using tax rates that have been enacted or substantively enacted by the reporting end date.
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
1
Accounting policies
(Continued)
- 16 -
Deferred tax
Deferred tax liabilities are generally recognised for all timing differences and deferred tax assets are recognised to the extent that it is probable that they will be recovered against the reversal of deferred tax liabilities or other future taxable profits. Such assets and liabilities are not recognised if the timing difference arises from goodwill or from the initial recognition of other assets and liabilities in a transaction that affects neither the tax profit nor the accounting profit.
The carrying amount of deferred tax assets is reviewed at each reporting end date and reduced to the extent that it is no longer probable that sufficient taxable profits will be available to allow all or part of the asset to be recovered. Deferred tax is calculated at the tax rates that are expected to apply in the period when the liability is settled or the asset is realised. Deferred tax is charged or credited in the profit and loss account, except when it relates to items charged or credited directly to equity, in which case the deferred tax is also dealt with in equity. Deferred tax assets and liabilities are offset when the company has a legally enforceable right to offset current tax assets and liabilities and the deferred tax assets and liabilities relate to taxes levied by the same tax authority.
1.10
Provisions
Provisions are recognised when the company has a legal or constructive present obligation as a result of a past event, it is probable that the company will be required to settle that obligation and a reliable estimate can be made of the amount of the obligation.
The amount recognised as a provision is the best estimate of the consideration required to settle the present obligation at the reporting end date, taking into account the risks and uncertainties surrounding the obligation. Where the effect of the time value of money is material, the amount expected to be required to settle the obligation is recognised at present value. When a provision is measured at present value, the unwinding of the discount is recognised as a finance cost in profit or loss in the period in which it arises.
1.11
Retirement benefits
The Company operates a defined contribution plan for its employees. A defined contribution plan is a pension plan under which the Company pays fixed contributions into a separate entity. Once the contributions have been paid the Company has no further payment obligations.
The contributions are recognised as an expense in profit or loss when they fall due. Amounts not paid are shown as a liability in the Balance sheet. The assets of the plan are held separately from the Company in independently administered funds.
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
1
Accounting policies
(Continued)
- 17 -
1.12
Share-based payments
When share options are awarded to employees, the fair value of the options at the date of grant is charged to profit or loss over the vesting period. Non-market vesting conditions are taken into account by adjusting the number of equity instruments expected to vest at each balance sheet date so that, ultimately, the cumulative amount recognised over the vesting period is based on the number of options that eventually vest. Market vesting conditions are factored into the fair value of the options granted. The cumulative expense is not adjusted for failure to achieve a market vesting condition.
The fair value of the award also takes into account non-vesting conditions. These are either factors beyond the control of either party (such as a target based on an index) or factors which are within the control of one or other of the parties (such as the Company keeping the scheme open or the employee maintaining any contributions required by the scheme).
Where the terms and conditions of options are modified before they vest, the increase in the fair value of the options, measured immediately before and after the modification, is also charged to profit or loss over the remaining vesting period.
Where equity instruments are granted to persons other than employees, profit or loss is charged with fair value of goods and services received.
1.13
Leases
As lessee
Leased assets: the Company as lessee
Assets obtained under hire purchase contracts and finance leases are capitalised as tangible fixed assets. Assets acquired by finance lease are depreciated over the shorter of the lease term and their useful lives. Assets acquired by hire purchase are depreciated over their useful lives. Finance leases are those where substantially all of the benefits and risks of ownership are assumed by the company. Obligations under such agreements are included in creditors net of the finance charge allocated to future periods. The finance element of the rental payment is charged to profit or loss so as to produce a constant periodic rate of charge on the net obligation outstanding in each period.
Operating leases: the Company as lessee
Rentals paid under operating leases are charged to profit or loss on a straight-line basis over the lease term.
Benefits received and receivable as an incentive to sign an operating lease are recognised on a straight-line basis over the lease term, unless another systematic basis is representative of the time pattern of the lessee's benefit from the use of the leased asset.
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
1
Accounting policies
(Continued)
- 18 -
1.14
Foreign exchange
Functional and presentation currency
The Company's functional and presentational currency is GBP.
Transactions and balances
Foreign currency transactions are translated into the functional currency using the spot exchange rates at the dates of the transactions.
At each period end foreign currency monetary items are translated using the closing rate. Non-monetary items measured at historical cost are translated using the exchange rate at the date of the transaction and non-monetary items measured at fair value are measured using the exchange rate when fair value was determined.
Foreign exchange gains and losses resulting from the settlement of transactions and from the translation at period-end exchange rates of monetary assets and liabilities denominated in foreign currencies are recognised in profit or loss except when deferred in other comprehensive income as qualifying cash flow hedges.
1.15
Investments in subsidiaries are measured at cost less accumulated impairment.
1.16
In the research phase of an internal project it is not possible to demonstrate that the project will generate future economic benefits and hence all expenditure on research shall be recognised as an expense when it is incurred. Intangible assets are recognised from the development phase of a project if and only if certain specific criteria are met in order to demonstrate the asset will generate probable future economic benefits and that its cost can be reliably measured. The capitalised development costs are subsequently amortised on a straight-line basis over their useful economic lives, which range from 3 to 6 years.
If it is not possible to distinguish between the research phase and the development phase of an internal project, the expenditure is treated as if it were all incurred in the research phase only.
1.17
Equity dividends are recognised when they become legally payable. Interim equity dividends are recognised when paid. Final equity dividends are recognised when approved by the shareholders at an annual general meeting.
2
Judgements and key sources of estimation uncertainty
Estimates and judgments are continually evaluated based on historical experience and other factors, including expectations of future events that are believed to be reasonable under the circumstances.
Key accounting estimates and assumptions are shown below.
Useful economic lives of tangible assets:-
The annual depreciation charge for tangible assets is sensitive to changes in the estimated useful economic lives and residual values of the assets. The useful economic lives and residual values are re-assessed annually. They are amended when necessary to reflect current estimates, based on technological advancement, future investments, economic utilisation and the physical condition of the assets.
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
- 19 -
3
Turnover and other operating income
2025
2024
£
£
Turnover analysed by geographical market
United Kingdom
3,192,304
3,038,692
Rest of Europe
2,240,323
3,656,189
Rest of the world
5,018,491
4,342,308
10,451,118
11,037,189
2025
2024
£
£
Other operating income
Research and development tax credit
1,086,482
1,141,639
4
Operating loss
2025
2024
Operating loss for the year is stated after charging:
£
£
Exchange losses
30,862
566
Research and development charged as an expense
5,431,594
6,409,878
Fees payable to the company's auditor for the audit of the company's financial statements
16,320
16,000
Share-based payments
3,228
4,448
Operating lease charges
1,715,128
1,757,050
5
Employees
The average monthly number of persons (including directors) employed by the company during the year was:
2025
2024
Number
Number
Employees, including the directors
100
117
Their aggregate remuneration comprised:
2025
2024
£
£
Wages and salaries
4,729,448
5,374,526
Social security costs
582,892
583,206
Pension costs
718,646
800,368
6,030,986
6,758,100
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
- 20 -
6
Directors' remuneration
2025
2024
£
£
Remuneration for qualifying services
395,501
383,718
Company pension contributions to defined contribution schemes
13,022
12,492
408,523
396,210
The number of directors for whom retirement benefits are accruing under defined contribution schemes amounted to 1 (2024 - 0).
The number of directors who exercised share options during the year was 1 (2024 - 1).
Remuneration disclosed above include the following amounts paid to the highest paid director:
2025
2024
£
£
Remuneration for qualifying services
125,440
134,467
Company pension contributions to defined contribution schemes
-
-
The highest paid director has exercised share options during the year.
7
Interest receivable and similar income
2025
2024
£
£
Interest income
Interest on bank deposits
7,099
16,150
8
Interest payable and similar expenses
2025
2024
£
£
Interest on financial liabilities measured at amortised cost
Interest on loans
19,336
-
Other finance costs
Interest on finance leases and hire purchase contracts
37,737
62,416
57,073
62,416
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
- 21 -
9
Taxation
2025
2024
£
£
Current tax
UK corporation tax on profits for the current period
37,797
(189,244)
Deferred tax
Origination and reversal of timing differences
(184,827)
(155,181)
Total tax credit
(147,030)
(344,425)
2025
2024
£
£
Loss before taxation
(712,072)
(1,391,572)
Expected tax credit based on the standard rate of corporation tax in the UK of 25.00% (2024: 25.00%)
(178,018)
(347,893)
Tax effect of expenses that are not deductible in determining taxable profit
14,887
27,373
Unutilised tax credits
16,101
Surrender of tax losses for tax credit
137,039
Adjustments to deferred tax charge in respect to prior periods
(10,082)
Adjustment in research and development tax credit leading to an increase (decrease) in the tax charge
-
(150,862)
Taxation credit for the year
(147,030)
(344,425)
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
- 22 -
10
Tangible fixed assets
Short-term leasehold improvements
Plant and machinery
Fixtures and fittings
Office equipment
Total
£
£
£
£
£
Cost
At 1 January 2025
1,060,413
7,018,249
135,062
497,015
8,710,739
Additions
1,805
133,475
2,849
138,129
Disposals
(31,336)
(31,336)
At 31 December 2025
1,062,218
7,120,388
137,911
497,015
8,817,532
Depreciation and impairment
At 1 January 2025
435,493
3,533,413
81,937
366,276
4,417,119
Depreciation charged in the year
164,087
763,566
17,631
65,091
1,010,375
Eliminated in respect of disposals
(27,286)
(27,286)
At 31 December 2025
599,580
4,269,693
99,568
431,367
5,400,208
Carrying amount
At 31 December 2025
462,638
2,850,695
38,343
65,648
3,417,324
At 31 December 2024
624,920
3,484,836
53,125
130,739
4,293,620
Included within tangible fixed assets are assets held under finance leases or hire purchase contracts, as follows:
2025
2024
£
£
Plant and machinery
888,294
1,267,148
11
Fixed asset investments
2025
2024
Notes
£
£
Investments in subsidiaries
12
1,000
1,000
12
Subsidiaries
Details of the company's subsidiaries at 31 December 2025 are as follows:
Name of undertaking
Registered office
Class of
% Held
shares held
Direct
NCE Discovery Limited
Chesterford Research Park, Little Chesterford, Saffron Walden, CB10 1XL
Ordinary
100.00
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
- 23 -
13
Stocks
2025
2024
£
£
Raw materials and consumables
215,472
192,499
14
Debtors
2025
2024
Amounts falling due within one year:
£
£
Trade debtors
909,405
920,990
Other debtors
502,605
344,369
Tax recoverable
879,918
1,045,473
Prepayments and accrued income
1,060,581
962,962
3,352,509
3,273,794
2025
2024
Amounts falling due after more than one year:
£
£
Corporation tax recoverable
1,189,064
1,020,297
Total debtors
4,541,573
4,294,091
15
Creditors: amounts falling due within one year
2025
2024
Notes
£
£
Obligations under finance leases
17
228,358
347,589
Other borrowings
611,800
Trade creditors
919,805
705,882
Amounts owed to group undertakings
1,000
1,000
Taxation and social security
137,452
187,425
Other creditors
80,066
112,303
Accruals and deferred income
855,949
1,675,282
2,834,430
3,029,481
Other borrowings are secured by way of a fixed and floating charge over the assets of the company.
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
- 24 -
16
Creditors: amounts falling due after more than one year
2025
2024
Notes
£
£
Obligations under finance leases
17
92,033
273,234
Obligations under finance leases are secured on the assets concerned.
17
Finance lease obligations
2025
2024
Amounts due:
£
£
Within one year
228,358
347,589
After more than one year
92,033
273,234
320,391
620,823
2025
2024
Future minimum lease payments due under finance leases:
£
£
Within one year
244,455
379,574
In two to five years
97,458
289,706
341,913
669,280
Less: future finance charges
(21,522)
(48,457)
320,391
620,823
18
Deferred taxation
The following are the major deferred tax liabilities and assets recognised by the company and movements thereon:
Liabilities
Liabilities
2025
2024
Balances:
£
£
Accelerated capital allowances
727,654
917,021
Tax losses
(611,268)
(611,268)
Other short term timing differences
(11,394)
(15,934)
104,992
289,819
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
18
Deferred taxation
(Continued)
- 25 -
2025
Movements in the year:
£
Liability at 1 January 2025
289,819
Credit to profit or loss
(184,827)
Liability at 31 December 2025
104,992
The net deferred tax expected to reverse next year is £207,629 (2024 - £163,337) relating to the timing differences on tangible fixed assets.
19
Retirement benefit schemes
2025
2024
Defined contribution schemes
£
£
Charge to profit or loss in respect of defined contribution schemes
718,646
800,368
The company operates a defined contribution pension scheme for all qualifying employees. The assets of the scheme are held separately from those of the company in an independently administered fund.
Contributions totalling £64,113 (2024 - £60,781) were payable to the fund at the balance sheet date and are included in creditors.
20
Share-based payment transactions
The company operates a share option scheme for executives and employees.
Options granted to executives are only exercisable when vested. Vesting typically occurs in 3 equal tranches starting on the first anniversary of grant. All options lapse after a period of ten years and are forfeited if an employee leaves the company and does not exercise the options vested within a specified period.
Details of options are shown below.
Number of share options
Weighted average exercise price
2025
2024
2025
2024
Number
Number
£
£
Outstanding at 1 January 2025
44,550
55,450
1.27
1.47
Granted
10,000
2,500
0.76
3.16
Forfeited
0.96
1.29
Exercised
2.83
2.48
Outstanding at 31 December 2025
27,550
44,550
1.33
1.27
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
20
Share-based payment transactions
(Continued)
- 26 -
At the balance sheet date 17,050 options had vested.
The fair value of equity-settled share options is estimated at the date of grant using the Black Scholes model which is considered to be most appropriate for the type of share granted.
Liabilities and expenses
During the year, the company recognised total share-based payment expenses of £3,228 (2024 - £4,448) which related to equity settled share based payment transactions.
The company has previously issued warrants. 16,429 remain outstanding at 31 December 2025. These warrants entitle holders to subscribe for £0.01 ordinary shares in the company at an exercise price of £0.81 and expire on 30 November 2030.
21
Share capital
2025
2024
2025
2024
Ordinary share capital
Number
Number
£
£
Issued and fully paid
Ordinary A shares of 1p each
325,042
324,374
3,251
3,244
Ordinary B shares of 1p each
213,494
213,494
2,135
2,135
538,536
537,868
5,386
5,379
2025
2024
2025
2024
Preference share capital
Number
Number
£
£
Issued and fully paid
Preference C shares of 1p each
26,179
26,179
262
262
Preference shares classified as equity
262
262
Total equity share capital
5,648
5,641
The preference shares entitle the shareholders to receive a dividend of 8% of the issue price, payable annually on 31 May. The dividends are cumulative in the event that a dividend is not declared in any year. The preference shares have no voting rights and are non redeemable. No preference dividends have been paid since May 2023 and the cumulative dividend unpaid is £139,860.
During the year the company issued 668 (2024 - 2,900) Ordinary A shares to employees as they exercised share options. Proceeds of £1,890 (2024 - £7,201) were received.
22
Reserves
Share premium
The reserve records the amount above the nominal value received for shares issued, less transaction costs.
Profit and loss
This reserve includes all current and prior period retained profits and losses.
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
- 27 -
23
Operating lease commitments
As lessee
At the reporting end date the company had outstanding commitments for future minimum lease payments under non-cancellable operating leases, which fall due as follows:
2025
2024
£
£
Within 1 year
1,685,283
1,838,490
Years 2-5
2,330,188
4,015,470
4,015,471
5,853,960
As lessor - operating leases
2025
2024
Future amounts receivable under operating leases:
£
£
Within 1 year
273,881
Years 2-5
479,292
753,173
-
24
Related party transactions
Remuneration of key management personnel
The remuneration of key management personnel is as follows.
2025
2024
£
£
Aggregate compensation
1,311,874
1,113,786
Transactions with related parties
During the year the company entered into the following transactions with entities in which directors held an interest:
Purchases
Purchases
2025
2024
£
£
Investor monitoring fees
36,000
36,000
Consultancy and other fees
37,945
32,841
DOMAINEX LIMITED
NOTES TO THE FINANCIAL STATEMENTS (CONTINUED)
FOR THE YEAR ENDED 31 DECEMBER 2025
24
Related party transactions
(Continued)
- 28 -
The following amounts were outstanding at the reporting end date:
2025
2024
Amounts due to related parties
£
£
Investor monitoring fees
-
4,500
Consultancy and other fees
2,226
4,696
25
Cash absorbed by operations
2025
2024
£
£
Loss after taxation
(565,042)
(1,047,147)
Adjustments for:
Taxation credited
(147,030)
(344,425)
Finance costs
57,073
62,416
Investment income
(7,099)
(16,150)
Equity settled shared based payments
3,228
4,448
Gain on disposal of tangible fixed assets
(10,451)
-
Depreciation and impairment of tangible fixed assets
1,010,375
1,049,495
Movements in working capital:
(Increase)/decrease in stocks
(22,973)
44,884
(Increase)/decrease in debtors
(285,280)
(1,300,130)
(Decrease)/increase in creditors
(687,620)
369,532
Cash absorbed by operations
(654,819)
(1,177,077)
26
Analysis of changes in net funds/(debt)
1 January 2025
Cash flows
New leases
31 December 2025
£
£
£
£
Cash at bank and in hand
973,530
(515,162)
-
458,368
Borrowings excluding overdrafts
-
(611,800)
-
(611,800)
Lease liabilities
(620,823)
359,427
(58,995)
(320,391)
352,707
(767,535)
(58,995)
(473,823)
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