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Company No: 12085226 (England and Wales)

MODERN SYNTHESIS LIMITED

Financial Statements
For the financial year ended 31 December 2025
Pages for filing with the registrar

MODERN SYNTHESIS LIMITED

Financial Statements

For the financial year ended 31 December 2025

Contents

MODERN SYNTHESIS LIMITED

STATEMENT OF FINANCIAL POSITION

As at 31 December 2025
MODERN SYNTHESIS LIMITED

STATEMENT OF FINANCIAL POSITION (continued)

As at 31 December 2025
Note 2025 2024
£ £
Fixed assets
Intangible assets 5 3,158,241 2,014,845
Tangible assets 6 230,210 227,993
3,388,451 2,242,838
Current assets
Debtors
- due within one year 7 380,778 315,729
- due after more than one year 7 104,371 104,371
Cash at bank and in hand 1,850,047 3,855,736
2,335,196 4,275,836
Creditors: amounts falling due within one year 8 ( 78,422) ( 43,888)
Net current assets 2,256,774 4,231,948
Total assets less current liabilities 5,645,225 6,474,786
Provision for liabilities 9 ( 75,712) ( 72,800)
Net assets 5,569,513 6,401,986
Capital and reserves
Called-up share capital 10 102 102
Share premium account 8,409,666 8,409,666
Profit and loss account ( 2,840,255 ) ( 2,007,782 )
Total shareholder's funds 5,569,513 6,401,986

The financial statements have been prepared and delivered in accordance with the provisions applicable to companies subject to the small companies regime and a copy of the Profit and Loss Account has not been delivered.

The financial statements of Modern Synthesis Limited (registered number: 12085226) were approved and authorised for issue by the Board of Directors. They were signed on its behalf by:

J K Keane
Director

25 September 2026

MODERN SYNTHESIS LIMITED

NOTES TO THE FINANCIAL STATEMENTS

For the financial year ended 31 December 2025
MODERN SYNTHESIS LIMITED

NOTES TO THE FINANCIAL STATEMENTS

For the financial year ended 31 December 2025
1. Accounting policies

The principal accounting policies are summarised below. They have all been applied consistently throughout the financial year and to the preceding financial year, unless otherwise stated.

General information and basis of accounting

Modern Synthesis Limited (the company) is a private company, limited by shares, incorporated in the United Kingdom under the Companies Act 2006 and is registered in England and Wales. The address of the company's registered office is Modern Synthesis, Unit 12, Zennor Trade Park Zennor Road, Balham, London, SW12 0PS, United Kingdom.

The financial statements have been prepared under the historical cost convention, modified to include certain items at fair value, and in accordance with Section 1A of Financial Reporting Standard 102 (FRS 102) ‘The Financial Reporting Standard applicable in the UK and Republic of Ireland’ issued by the Financial Reporting Council and the requirements of the Companies Act 2006 as applicable to companies subject to the small companies regime.

The financial statements are presented in pounds sterling which is the functional currency of the company and rounded to the nearest £.

Going concern

The company remains in the pre-commercial scale-up phase and incurred a loss of £832,473 during the year (2024: £485,255). At 31 December 2025, the company had net assets of £5,569,513 (2024: £6,401,986) and cash at bank and in hand of £1,850,047 (2024: £3,855,736).

The directors have reviewed the company's cash flow forecasts covering a period of at least 12 months from the date of approval of the financial statements. In preparing these forecasts, the directors have considered existing cash resources and funding secured subsequent to the year end. Based on this assessment, the directors have a reasonable expectation that the company has adequate resources to continue in operational existence for the foreseeable future and therefore continue to adopt the going concern basis in preparing these financial statements.

Foreign currency

Transactions in foreign currencies are recorded at the rate of exchange at the date of the transaction. Monetary assets and liabilities denominated in foreign currencies at the reporting date are reported at the rates of exchange prevailing at that date.

Exchange differences are recognised in the Profit and Loss Account in the period in which they arise except for exchange differences arising on gains or losses on non-monetary items which are recognised in the Statement of Comprehensive Income.

Turnover

Turnover is recognised at the fair value of the consideration received or receivable for goods and services provided in the normal course of business, and is shown net of VAT and other sales related taxes. The fair value of consideration takes into account trade discounts, settlement discounts and volume rebates.

Turnover consists of sales from biomaterial manufacturing and research and development contracts.

Employee benefits

Defined contribution schemes
The company operates a defined contribution scheme. The amount charged to the Profit and Loss Account in respect of pension costs and other post-retirement benefits is the contributions payable in the financial year. Differences between contributions payable in the financial year and contributions actually paid are included as either accruals or prepayments in the Statement of Financial Position.

Taxation

Current tax
Current tax is provided at amounts expected to be paid (or recoverable) using the tax rates and laws that have been enacted or substantively enacted at the reporting date.

Deferred tax
Deferred tax arises as a result of including items of income and expenditure in taxation computations in periods different from those in which they are included in the company's financial statements. Deferred tax is provided in full on timing differences which result in an obligation to pay more or less tax at a future date, at the average tax rates that are expected to apply when the timing differences reverse, based on current tax rates and laws. Deferred tax assets and liabilities are not discounted.

The carrying amount of deferred tax assets is reviewed at each reporting date and a valuation allowance is set up against deferred tax assets so that the net carrying amount equals the highest amount that is more likely than not to be recovered based on current or future taxable profit.

Intangible assets

Intangible assets are stated at cost or valuation, net of amortisation and any provision for impairment. Amortisation is provided on all intangible assets at rates to write off the cost or valuation of each asset over its expected useful life as outlined below.

Capitalised development costs are amortised over their estimated useful economic lives once the underlying product or process is available for commercial use. Prior to that date, the assets are reviewed for indicators of impairment at each reporting date.

Development costs not amortised
Trademarks, patents and licences 0 - 20 years straight line
Research and development

Research expenditure is written off as incurred. Development expenditure is also written off, except where the directors are satisfied as to the technical, commercial and financial viability of individual projects. In such cases, the identifiable expenditure is capitalised as an intangible asset and amortised over the period during which the company is expected to benefit. A provision is made for any impairment.

Trademarks, patents and licences

Separately acquired patents and trademarks are included at cost and amortised in equal annual instalments over the term that they protect. A provision is made for any impairment.

Tangible fixed assets

Tangible fixed assets are stated at cost or valuation, net of depreciation and any provision for impairment. Depreciation is provided on all tangible fixed assets, other than investment property and freehold land, at rates calculated to write off the cost or valuation, less estimated residual value, of each asset on a straight-line or reducing balance basis over its expected useful life, as follows:

Land and buildings 5 years straight line
Plant and machinery etc. 5 years straight line
Impairment of assets

Assets, other than those measured at fair value, are assessed for indicators of impairment at each Statement of Financial Position date. If there is objective evidence of impairment, an impairment loss is recognised in the Statement of Comprehensive Income.

Financial instruments

The Company only enters into basic financial instruments and transactions that result in the recognition of financial assets and liabilities like trade and other debtors and creditors, loans from banks and other third parties, loans to and from related parties and investments in non-puttable ordinary shares.

Financial assets
Basic financial assets, including trade and other debtors, and amounts due from related companies, are initially recognised at transaction price, unless the arrangement constitutes a financing transaction, where the transaction is measured at the present value of the future receipts discounted at a market rate of interest.

Such assets are subsequently carried at amortised cost using the effective interest method.

At the end of each reporting period financial assets measured at amortised cost are assessed for objective evidence of impairment. If an asset is impaired the impairment loss is the difference between the carrying amount and the present value of the estimated cash flows discounted at the asset’s original effective interest rate. The impairment loss is recognised in the Statement of Comprehensive Income.

Financial assets are derecognised when (a) the contractual rights to the cash flows from the asset expire or are settled, or (b) substantially all the risks and rewards of the ownership of the asset are transferred to another party or (c) control of the asset has been transferred to another party who has the practical ability to unilaterally sell the asset to an unrelated third party without imposing additional restrictions.

Financial liabilities
Basic financial liabilities, including trade and other creditors and accruals, are initially recognised at transaction price, unless the arrangement constitutes a financing transaction, where the debt instrument is measured at the present value of the future receipts discounted at a market rate of interest.

Trade creditors are obligations to pay for goods or services that have been acquired in the ordinary course of business from suppliers. Trade creditors are classified as current liabilities if payment is due within one year or less. If not, they are presented as non-current liabilities. Trade creditors are recognised initially at transaction price and subsequently measured at amortised cost using the effective interest method.

Financial liabilities are derecognised when the liability is extinguished, that is when the contractual obligation is discharged, cancelled or expires.

Financial assets and liabilities are offset and the net amounts presented in the financial statements when there is a legally enforceable right to set off the recognised amounts and there is an intention to settle on a net basis or to realise the asset and settle the liability simultaneously.

Equity instruments
Equity instruments issued by the company are recorded at the fair value of cash or other resources received or receivable, net of direct issue costs. If payment is deferred and the time value of money is material, the initial measurement is on a present value basis. Dividends payable on equity instruments are recognised as liabilities once they are no longer at the discretion of the company.

Provisions

Provisions are recognised when the company has a present obligation (legal or constructive) as a result of a past event, it is probable that the company will be required to settle that obligation and a reliable estimate can be made of the amount of the obligation.

The amount recognised as a provision is the best estimate of the consideration required to settle the present obligation at the reporting date, taking into account the risks and uncertainties surrounding the obligation. Where a provision is measured using the cash flows estimated to settle the present obligation, its carrying amount is the present value of those cash flows (when the effect of the time value of money is material).

When some or all of the economic benefits required to settle a provision are expected to be recovered from a third party, a receivable is recognised as an asset if it is virtually certain that reimbursement will be received and the amount of the receivable can be measured reliably.

Grants

Government grants are recognised under the performance model and measured at the fair value of the amount received or receivable. Grant income is recognised in other operating income when the related performance conditions have been satisfied, provided there is reasonable assurance that the company will comply with any conditions attached to the grant and that the grant will be received.

2. Critical accounting judgements and key sources of estimation uncertainty

In the application of the company’s accounting policies, the directors are required to make judgements that have a significant impact on the amounts recognised. The following are the critical judgements that the directors have made in the process of applying the company’s accounting policies and that have the most significant effect on the amounts recognised in the financial statements.

Wages costs have been capitalised based on the percentage of staff time dedicated to the development of biomaterial technology. This percentage is determined through management's judgement, using estimates of time spent during the financial year on design improvements and technological development.

Management exercises judgement in assessing whether there are indicators that the capitalised development costs may be impaired. Where indicators are identified, the recoverable amount is determined by reference to the higher of fair value less costs to sell and value in use. The value-in-use assessment requires estimates of future commercial revenues, margins, cash flows, the timing of commercialisation and an appropriate discount rate. Changes in these assumptions could result in a material adjustment to the carrying amount of the development costs.

3. Prior year adjustment

Comparative figures have been re-presented to reclassify grant income of £328,593 from revenue to other operating income. The reclassification has no impact on profit for the year or net assets.

4. Employees

2025 2024
Number Number
Monthly average number of persons employed by the company during the year, including directors 25 23

5. Intangible assets

Development costs Trademarks, patents
and licences
Total
£ £ £
Cost
At 01 January 2025 1,979,075 35,770 2,014,845
Additions 1,119,291 24,105 1,143,396
At 31 December 2025 3,098,366 59,875 3,158,241
Accumulated amortisation
At 01 January 2025 0 0 0
At 31 December 2025 0 0 0
Net book value
At 31 December 2025 3,098,366 59,875 3,158,241
At 31 December 2024 1,979,075 35,770 2,014,845

The directors have chosen to recognise development spending relating to innovation in the biomaterial manufacturing processes which is believed to give rise to future economic inflows to the company. No amortisation has been recognised to 31 December 2025 as the company has not yet started full commercial production.

Patents are filed, pending and further applications planned based on scientific discovery to date. No amortisation has been recognised to 31 December 2025 as the patents have not yet been granted.

6. Tangible assets

Land and buildings Plant and machinery etc. Total
£ £ £
Cost
At 01 January 2025 299,174 172,303 471,477
Additions 28,222 81,772 109,994
At 31 December 2025 327,396 254,075 581,471
Accumulated depreciation
At 01 January 2025 177,671 65,813 243,484
Charge for the financial year 63,174 44,603 107,777
At 31 December 2025 240,845 110,416 351,261
Net book value
At 31 December 2025 86,551 143,659 230,210
At 31 December 2024 121,503 106,490 227,993

7. Debtors

2025 2024
£ £
Debtors: amounts falling due within one year
Trade debtors 24,495 0
Prepayments and accrued income 40,717 83,560
VAT recoverable 27,406 21,632
Corporation tax 288,160 210,426
Other debtors 0 111
380,778 315,729
Debtors: amounts falling due after more than one year
Other debtors 104,371 104,371

8. Creditors: amounts falling due within one year

2025 2024
£ £
Trade creditors 14,757 12,583
Amounts owed to parent undertakings 16,950 18,213
Other taxation and social security 5,000 0
Other creditors 41,715 13,092
78,422 43,888

9. Provision for liabilities

2025 2024
£ £
Other provisions 75,712 72,800

10. Called-up share capital

2025 2024
£ £
Allotted, called-up and fully-paid
102 Ordinary shares of £ 1.00 each 102 102

11. Financial commitments

Commitments

Total future minimum lease payments under non-cancellable operating leases are as follows:

2025 2024
£ £
Within one year 115,968 115,968
Between one and five years 64,496 180,464
180,464 296,432

Pensions

The company operates a defined contribution pension scheme for the directors and employees. The assets of the scheme are held separately from those of the company in an independently administered fund.

2025 2024
£ £
Unpaid contributions due to the fund (inc. in other creditors) 9,637 7,510

12. Related party transactions

The company has availed of the exemption provided in FRS 102 Section 33 Related Party Disclosures not to disclose transactions entered into with fellow group companies that are wholly owned within the group of companies of which the company is a wholly owned member.

13. Audit Opinion

The auditor's report on the accounts for the financial year ended 31 December 2025 was unqualified.

The audit report was signed by Nadeem Kassim FCCA on behalf of BKL Audit LLP.

14. Ultimate controlling party

The immediate and ultimate Parent Undertaking is Modern Synthesis PBC, which is an entity incorporated in the United States of America.

In the opinion of the directors there is no ultimate controlling party.