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REGISTERED NUMBER: 09563670 (England and Wales)















FINANCIAL STATEMENTS FOR THE YEAR ENDED 31 DECEMBER 2025

FOR

SOLENO THERAPEUTICS UK LTD

SOLENO THERAPEUTICS UK LTD (REGISTERED NUMBER: 09563670)






CONTENTS OF THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 31 DECEMBER 2025




Page

Company information 1

Balance sheet 2

Notes to the financial statements 3


SOLENO THERAPEUTICS UK LTD

COMPANY INFORMATION
FOR THE YEAR ENDED 31 DECEMBER 2025







Directors: Mr M C Abernethy
Mr D L Bradfute
Mr D M Lippoldt





Registered office: Suite 4, 7th Floor
50 Broadway
London
SW1H 0DB





Registered number: 09563670 (England and Wales)





Auditors: Nortons Assurance Limited
Chartered Accountants & Statutory Auditor
Second Floor
NOW Building
Thames Valley Park
Reading
Berkshire
RG6 1RB

SOLENO THERAPEUTICS UK LTD (REGISTERED NUMBER: 09563670)

BALANCE SHEET
31 DECEMBER 2025

31/12/25 31/12/24
(Unaudited)
Notes $ $
CURRENT ASSETS
Debtors 4 759,883 1,144,401
Cash at bank 11,577 193,173
771,460 1,337,574
CREDITORS
Amounts falling due within one year 5 (293,708 ) (1,013,756 )
NET CURRENT ASSETS 477,752 323,818
TOTAL ASSETS LESS CURRENT
LIABILITIES

477,752

323,818

CAPITAL AND RESERVES
Called up share capital 152 152
Retained earnings 477,600 323,666
477,752 323,818

The financial statements have been prepared and delivered in accordance with the provisions applicable to companies subject to the small companies regime.

In accordance with Section 444 of the Companies Act 2006, the Income statement has not been delivered.

The financial statements were approved by the Board of Directors and authorised for issue on 1 October 2026 and were signed on its behalf by:





Mr M C Abernethy - Director


SOLENO THERAPEUTICS UK LTD (REGISTERED NUMBER: 09563670)

NOTES TO THE FINANCIAL STATEMENTS
FOR THE YEAR ENDED 31 DECEMBER 2025

1. STATUTORY INFORMATION

Soleno Therapeutics UK Ltd is a private company, limited by shares , registered in England and Wales. The company's registered number and registered office address can be found on the Company Information page.

The company's functional and presentational currency is US Dollar ($) and the financial statements have been rounded to the nearest Dollar ($).

2. ACCOUNTING POLICIES

Basis of preparing the financial statements
These financial statements have been prepared in accordance with Financial Reporting Standard 102 "The Financial Reporting Standard applicable in the UK and Republic of Ireland" including the provisions of Section 1A "Small Entities" and the Companies Act 2006. The financial statements have been prepared under the historical cost convention.

Related party exemption
The company has taken advantage of exemption, under the terms of Financial Reporting Standard 102 'The Financial Reporting Standard applicable in the UK and Republic of Ireland', not to disclose related party transactions with wholly owned subsidiaries within the group.

Turnover
Turnover represents income earned from the parent company calculated on a cost plus basis, excluding Value Added Tax.

Financial instruments
The company has elected to apply the provisions of Section 11 'Basic Financial Instruments' and Section 12 'Other Financial Instruments Issues' of FRS102 to all of its financial instruments.

Financial instruments are recognised in the company's balance sheet when the company becomes party to the contractual provisions of the instrument.

Financial assets and liabilities are offset, with the net amounts presented in the financial statements, when there is a legally enforceable right to set off the recognised amounts and there is an intention to settle on a net basis or to realise the asset and settle the liability simultaneously.

Classification of financial liabilities
Financial liabilities and equity instruments are classified according to the substance of the contractual arrangements entered into.

Basic financial liabilities
Basic financial liabilities, including creditors, and loans from fellow group companies are initially recognised at transaction price.

Trade creditors are obligations to pay for goods or services that have been acquired in the ordinary course of business from suppliers. Amounts payable are classified as current liabilities if payment is due within one year or less. If not, they are presented as non-current liabilities. Trade creditors are initially recognised at transaction price.

Taxation
Taxation for the year comprises current tax. Tax is recognised in the Income Statement, except to the extent that it relates to items recognised in other comprehensive income or directly in equity.

Current taxation assets and liabilities are not discounted.

Current tax is recognised at the amount of tax payable using the tax rates and laws that have been enacted or substantively enacted by the balance sheet date.

Foreign currencies
Assets and liabilities in foreign currencies are translated into dollars (USD) at the rates of exchange ruling at the balance sheet date. Transactions in foreign currencies are translated into dollars (USD) at the rate of exchange ruling at the date of transaction. Exchange differences are taken into account in arriving at the operating result.

SOLENO THERAPEUTICS UK LTD (REGISTERED NUMBER: 09563670)

NOTES TO THE FINANCIAL STATEMENTS - continued
FOR THE YEAR ENDED 31 DECEMBER 2025

2. ACCOUNTING POLICIES - continued

Going concern
The company is reliant on the ongoing support of its parent company to meet its day to day liabilities. The directors have received confirmation of continued financial support for the foreseeable future from its ultimate parent company, Neurocrine Biosciences, Inc., thus the directors have a reasonable expectation that the Company has adequate resources to continue in operational existence for the foreseeable future and continue to adopt the going concern basis of accounting in preparing the annual financial statements.

3. EMPLOYEES AND DIRECTORS

The average number of employees during the year was NIL (2024 - NIL).

4. DEBTORS: AMOUNTS FALLING DUE WITHIN ONE YEAR
31/12/25 31/12/24
(Unaudited)
$ $
Amounts owed by group undertakings 695,739 1,137,983
Other debtors 64,144 6,418
759,883 1,144,401

5. CREDITORS: AMOUNTS FALLING DUE WITHIN ONE YEAR
31/12/25 31/12/24
(Unaudited)
$ $
Trade creditors 65,964 77,623
Tax 51,310 943
Accruals 176,434 935,190
293,708 1,013,756

6. DISCLOSURE UNDER SECTION 444(5B) OF THE COMPANIES ACT 2006

The Report of the auditors was unqualified.

Karen Cairns (Senior Statutory Auditor)
for and on behalf of Nortons Assurance Limited

7. RELATED PARTY DISCLOSURES

At the balance sheet date, the company's immediate and ultimate parent company was Soleno Therapeutics Inc, a company registered in the United States of America. Their registered office is located at 100 Marine Parkway, Suite 400, Redwood City, CA 94065, United States of America.

The parent of the smallest group for which consolidated financial statements are drawn up of which the company is a member is Soleno Therapeutics Inc.

8. POST BALANCE SHEET EVENTS

On 18 May 2026, the company's parent Soleno Therapeutics Inc, was acquired by Neurocrine Biosciences, Inc. At that date, Neurocrine Biosciences, Inc became the company's ultimate parent.